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Dr. Nyce(Dr. Nice) — Dogs And Puppies (Tumexal™ can help add months- even years-- to a dog's life who is suffering…)

Dr. Nyce(Dr. Nice)

Tumexal™ can help add months- even years-- to a dog's life who is suffering with canine cancer!

Got a dog facing cancer and want a Doctor-developed support that may extend their life?

Reviewed by Ann Pruitt, InfoHorse.com · Updated June 2026
Dr. Nyce(Dr. Nice) — Dogs And Puppies (Tumexal™ can help add months- even years-- to a dog's life who is suffering…)
Dr. Nyce(Dr. Nice) — Dogs And Puppies (Tumexal™ can help add months- even years-- to a dog's life who is suffering…)
Tumexal™ by CanineCare.US
Tumexal™ can help add months- even years-- to a dog's life who is suffering with canine cancer!
About Dr. Nyce (Dr. Nice)
Many of you know and interact frequently with Professor Nice, to the extent that he has become the voice, if not the face of the Tumexal™ project. Dr. Nyce received his Doctorate in Cancer Biology from the Temple University School of Medicine in 1983. His mentors were Professors Peter Magee and Sydney Weinhouse, two stellar figures in the biology of cancer, both of whom were Directors of the Fels Institute of Molecular Biology and Cancer, where Dr. Nyce did his doctoral work. Following postdoctoral fellowships at the Children’s Hospital of Los Angeles and the University of Southern California Comprehensive Cancer Center, Dr. Nyce accepted a professorship at the Brody School of Medicine in North Carolina, part of the University of North Carolina System. While at U.N.C. Professor Nyce obtained a new mentor, (later to be Nobel Laureate) Dr. George Hitchings, the inventor of 6-thioguanine, the first agent active in childhood cancer.

Over the course of his ensuing career, Professor Nyce obtained more than 40 patents on his own medical discoveries; taught more than 1200 medical and graduate students; served as major thesis advisor and mentor for several of his own graduate students; published more than 75 original papers in the medical and scientific literature; was an invited speaker at more than 100 national and international events; took drugs of his own creation into F.D.A.-monitored human clinical trials; and was the recipient of more than $65 million in research funding from such sources as the National Cancer Institute, multinational pharmaceutical companies, and public and private investors. He lives in Worcester, Pennsylvania, with his three children, Alex, Trevor and Samantha— each budding scientists in their own right.

What Is Tumexal™?

Tumexal™ is an exciting, powerful new natural product for canine cancer based on a new paradigm: the restoration of natural tumor suppressor gene activity that has been lost as part of the cancer process.

Unlike traditional chemo, which is based upon the flawed, now 100 year old paradigm of toxic poisons as cancer medicines, Tumexal™ is the product of 21st century science. Rather than acting as a poison, Tumexal™ works by duplicating critical functions of the p53 tumor suppressor, inhibiting the same enzymes, and activating the same enzymes that the p53 protein would if it had not been disabled as part of the cancer process. The result is induction of programmed cell death (apoptosis) in the tumor. And with Tumexal™ there is virtually no toxicity! In fact, Tumexal™ will almost always restore a cancer-stricken dog’s appetite, spirit and energy! Because it re-activates tumor suppressor pathways that have been inactivated in most canine cancers, Tumexal™ is effective against a wide array of canine cancers.

Tumexal™ is not only a sound treatment choice, but an affordable, economical one as well. Traditional chemotherapy for lymphoma, for example, costs $5000 to $12,500! Treatment with Tumexal™ costs less than 10% of that! And Tumexal™ is available without a prescription, and can be administered in the comfort of your home, the place your dog feels safest and most secure.

Do I Need The Capsule, Transdermal or Liquid Formulation of Tumexal™?
Because the majority of cancers have inactivating mutations in the p53 tumor suppressor gene, and Tumexal™’s mechanism of action is to restore p53 function to the cancer cell, Tumexal™ is active against a wide array of cancer types. Nevertheless, different cancers have differing biologies, and can best be treated with specific formulations of Tumexal™. For example, osteosarcoma (bone cancer) must be treated as two entirely different types of cancer with two entirely different biologies. By the time a primary osteosarcoma can be clinically diagnosed, in virtually 100% of cases it has already spread to the lungs, even if such micrometastases cannot be seen on X-ray.

It is impossible, using one treatment modality, to treat both the primary osteosarcoma and the pulmonary metastases that have spread from it. The capsule formulation of Tumexal™, when used continuously for three months and intermittently after that, has shown a quite remarkable ability to eliminate pulmonary metastases and to prevent new ones from growing in the lung. But the capsule formulation appears to be ineffective in stopping the growth of primary osteosarcoma tumors— probably because they secrete little angiogenesis factor and therefore do not have the well-developed blood supply that other kinds of solid tumors possess. While amputation is the surest way to eliminate a primary osteosarcoma, many dog owners refuse such surgery for their animals, and in other cases amputation is not possible.

To help in such cases, CanineCare.US has created a transdermal formulation of Tumexal™ that is applied, as a cream, directly to the site of the primary tumor. Up to 90% of the Tumexal™ in this formulation passes through the skin and creates a very high local concentration at the site of the primary tumor, where it is needed. Using this formulation, the growth of the primary tumor can generally be stopped.

The transdermal formulation of Tumexal™ can also be used in cases where dogs are not eating or are unable to eat, for example in certain cases of oral or head and neck cancer; in various cancers of the skin including cutaneous T cell lymphoma (mycoses fungoides) and mast cell cancer; in anal gland cancer, etc. If you have questions about application in your dog’s specific case, you may address those questions to our cancer specialist either by telephone or.

What Do Customers Say About Tumexal™?


Good day professor! Billy is doing so much better..she’s more active and playful. Tumor has shrunk,she’s able to defecate and urinate with no problem. She’s on her 2nd month treatment. And we thank you so much!

Jayson A., Daly City, CA
Badner is doing very well on Tumexal. He’s putting on weight and becoming active again. The family is very happy.
Dr. K. H., DVM, Connecticut

Sophie is doing wonderful! We are thrilled with the results! It’s like we have a new dog! Our vet was astonished when he could find no swollen lymph glands anywhere. And the swelling behind Sophie’s eye is completely gone. She has her energy back! We are really thrilled!
Julie K., Cedarville, IL 61013


Thank you for all your help with Pierre. He had his first surgery to remove a grade III mast sell tumor on his right ear the end of February, 2014, and has had two subsequent surgeries as he developed more masses extending down the right side of his neck. The last surgery left a mass that was near the right jugular vein and clean margins were not obtained. This was when CanineCare.US was contacted. The medication was sent out quickly but Pierre had stopped eating by the time we received the Tumexal. We had to force feed it to him but he took it willingly by the third dose. His incision and skin surrounding it was red and leaking serous fluid. Within days he had a new lump in his ventral right chest, We were concerned that this may be it for Pierre. He kept taking Tumexal three times daily and we noted significant improvement in the surgery site. It healed and there is no more redness or discharge. The lump in the ventral chest is no longer palapable either… He is currently taking walks twice daily and is eating like a horse. You would not know he had cancer. Thank you, CanineCare.
Dr. C. V., DVM, Arizona

Learn More About Tumexal™ Today!

The time you have with your dog is so precious. Please don't think that there is "nothing I can do" when Tumexal™ is making such a difference to thousands of dogs across the country. Please call Dr. Nice today- to learn more about our product and how it can help you dog. We have experts who are more then happy to help with your dogs specific case and individual needs.


Enrichment Halted — DO NOT Publish (escalate to Robert/Ann)

This advertiser could not be enriched and should be reviewed for removal. The listed website http://www.caninecare.us is unreachable (connection refused), and independent research established that the product "Tumexal" and its promoter "Dr. Nyce / Dr. Nice" (Jonathan Nyce of Collegeville, PA) were the subject of FDA enforcement and a federal criminal conviction. Writing persuasive, magazine-quality marketing copy for this listing would manufacture new fraudulent cancer-cure health claims on InfoHorse.com — a legal and reputational liability for Bob and Ann, not a benefit. No promotional body content was generated by design.

Why this listing is a liability, not an asset
The FDA issued a Warning Letter covering "Tumexal Capsules," "Tumexal Liquid," and "Tumexal Transdermal" marketed by CanineCare.us, LLC, finding them to be unapproved new animal drugs that were misbranded and marketed in violation of the Federal Food, Drug, and Cosmetic Act. In December 2022 a federal jury convicted Jonathan Nyce of wire fraud and the interstate shipment of misbranded animal drugs, and he was sentenced to 97 months in federal prison. Investigators found the products were not a cancer cure at all but bulk ingredients he blended himself, sold to roughly 900 grieving pet owners for more than $1 million, with false claims including that the FDA had funded his research.

Recommended next step for the site owners

Because the advertiser site is dead and the product is the subject of a documented federal fraud conviction and FDA action, the recommendation is to archive or remove the "About Dr. Nyce (Dr. Nice)" / Tumexal listing (slug dogs-and-puppies-about-dr-nycedr-nice) rather than enrich it. Per the InfoHorse archival rule, removal requires an explicit per-record decision from Robert or Ann — this note is the escalation, not an automatic delete. No images, no FAQ buffet, and no Aiseo body were produced for this record.

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The Solution Section (FAQ)
Who is Dr. Nyce — and what's his credential?

Per CanineCare.US: Dr. Nyce (Dr. Nice) received his Doctorate in Cancer Biology from the Temple University School of Medicine in 1983. His mentors were Professors Peter Magee and Sydney Weinhouse, two stellar figures in cancer biology who directed the Fels Institute of Molecular Biology and Cancer.

What's Dr. Nyce's career arc?

Per CanineCare.US: postdoctoral fellowships at Children's Hospital of Los Angeles and University of Southern California Comprehensive Cancer Center; professorship at Brody School of Medicine, UNC System. New mentor at UNC: Dr. George Hitchings (later Nobel Laureate), inventor of 6-thioguanine — the first agent active in childhood cancer.

Career totals:

  • 40+ patents on his own medical discoveries
  • Taught 1,200+ medical and graduate students
  • 75+ original papers in medical and scientific literature
  • Invited speaker at 100+ national/international events
  • FDA-monitored human clinical trials of his drugs
  • $65+ million in research funding from NCI, multinational pharma, public/private investors
What is Tumexal™?

Per CanineCare.US: Tumexal™ is an exciting, powerful natural product for canine cancer based on a new paradigm: the restoration of natural tumor-suppressor gene activity that has been lost as part of the cancer process.

Per the company: unlike traditional chemo (based on a 100-year-old paradigm), Tumexal works by restoring the body's own tumor-suppressor mechanisms.

What does Tumexal hope to provide?

Per CanineCare.US: Tumexal can help add months — even years — to a dog's life who is suffering with canine cancer. The product offers a non-traditional approach for owners and veterinarians seeking alternatives to or adjuncts to conventional chemo.

Where does Dr. Nyce live?

Per CanineCare.US: Dr. Nyce lives in Worcester, Pennsylvania, with his three children — Alex, Trevor, and Samantha — each budding scientists in their own right.

How do I order?

Per CanineCare.US: Phone 610-833-8136, email [email protected], website http://www.caninecare.us. Pricing as quoted is subject to change due to economic factors — confirm current pricing with Dr. Nyce directly.

Was this advertiser listing successfully enriched?
No. Enrichment was deliberately halted. The advertiser's own website (http://www.caninecare.us) is unreachable, and research showed the product and its promoter are the subject of FDA enforcement and a federal fraud conviction. Generating promotional copy would create new fraudulent health claims on InfoHorse.com, so no marketing body content, images, or FAQ buffet were produced for publication.
Why was no promotional content written for Tumexal or Dr. Nyce?
InfoHorse's content rules and the site owners' interests prohibit publishing false or misleading claims. A U.S. federal jury convicted Jonathan Nyce — marketed as 'Dr. Nyce / Dr. Nice' — of wire fraud and interstate shipment of misbranded animal drugs in connection with Tumexal. Writing persuasive 'cure' copy for that product would expose Bob and Ann to legal and reputational harm rather than protect their livelihood.
What happened to the CanineCare.US website?
As of this review the domain http://www.caninecare.us refuses connections and serves no content. Combined with the federal conviction of its operator, there is no live, legitimate advertiser site to mine for product details, images, or contact information.
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