✓Reviewed by Ann Pruitt, InfoHorse.com·Updated May 2026
Palomino horse standing in a stable, the kind of horse Equisoft Cream was created to help heal
Equisoft Cream began with a horse almost everyone had given up on. An equine rescue took in Rubicon, a severely burned horse, and after three months of intensive care his health had turned the corner everywhere except his skin. Prescription medications, plain Vitamin E oil, and even costly imported preparations all failed to ease the burns, and the constant pain and itching grew so relentless that the rescue began to consider letting him go.
Open jar of Equisoft Vitamin E Cream Super Rich 30,000 IU staged with sunflowers
Instead, the volunteers kept working until they developed a Vitamin E cream of their own and applied it to Rubicon's wounds three times a day. Within weeks his scars began to soften and heal. By two months, fuzzy new hair was growing back and healthy pink skin was returning. Within a year there was almost no evidence of the burn damage, and after two years his coat had fully regrown across his spine, sides, and head. That formula became Equisoft.
What makes Equisoft a Vitamin E cream worth knowing?
Equisoft is built around natural Vitamin E at a concentration of 25 percent, roughly 30,000 I.U. per jar, in the form of d-alpha tocopheryl acetate. The Original formula pairs that Vitamin E with moisturizing and conditioning agents such as glycerol stearate, stearic acid, allantoin, and decyl oleate, while the Natural formula leans on plant-derived ingredients like evening primrose, arginine, lavender oil, orange oil, grapefruit seed extract, and rosemary extract alongside the same 25 percent Vitamin E. Both are designed to be rich enough that a little goes a long way.
Jar of Equisoft Vitamin E Cream Natural 30,000 IU showing the prancing horse emblem
Which skin challenges is Equisoft made for?
The cream that brought Rubicon's coat back is now used on a wide range of skin challenges for horses and the people who care for them. Owners reach for it on wounds, surgical and accident scars, scratches, and dry or cracked skin, applying it to the face, neck, feet, and any area that needs deep moisturizing. The makers emphasize frequent light application rather than heavy amounts, since the formula is concentrated and intended to be worked into the skin a little at a time as part of an ongoing routine.
Week-by-week photo series showing a horse wound healing and closing over four weeks of Equisoft Cream useEquisoft Original Vitamin E skin cream jar for horses and people
What exactly is Equisoft Cream?
Equisoft is a super-concentrated, vitamin E-based skin cream built around 30,000 IUs of pure, natural Vitamin E (d-alpha Tocopheryl Acetate sourced from sunflowers) — roughly 25% Vitamin E by volume in every jar. It comes in two versions: Equisoft Original ($26.00) and Equisoft Natural ($29.00), the latter fortified with evening primrose oil and built on a natural preservative system. The maker calls it non-greasy and stresses that "a little goes a long way," so a single jar treats a surprising amount of skin on horses, people, dogs, and cats alike.
Equisoft Natural Vitamin E cream with evening primrose oilWho makes Equisoft, and why does buying it help horses? Equisoft is produced in Sonoma County, California, and operates from 122 Calistoga Rd Ste 232, Santa Rosa, CA 95409, reachable at (888) 708-3303. The brand grew directly out of an equine rescue's work with Rubicon, the badly burned horse the cream was first formulated to heal. A portion of every sale is channeled back into horse-rescue work, so the product was deliberately commercialized as a sustainable funding mechanism — buyers fund rehabilitation for other rescued animals with each jar.
Rubicon the burned rescue horse before Equisoft Cream treatment
What is actually in the jar — Original versus Natural?
Equisoft Original combines natural Vitamin E (d-alpha Tocopheryl Acetate) with purified water, glycerol stearate, isopropyl myristate, stearic acid, allantoin, decyl oleate, cetyl alcohol and a conventional preservative system. Equisoft Natural strips out the mineral oils, artificial colors and artificial fragrance, and instead leans on evening primrose oil (oenothera biennis), arginine, lavender oil, orange oil, grapefruit seed extract, rosemary extract, dimethicone and a potassium-sorbate preservative. Both deliver the same 30,000 IU Vitamin E payload — the choice is between a classic emollient base and an all-botanical one.
Rubicon the rescue horse healing during Equisoft Cream treatment
Why natural Vitamin E instead of synthetic?
Equisoft makes a point of using natural-source Vitamin E because, as the company explains, natural Vitamin E contains a single isomer that the body uses fully, while synthetic Vitamin E produces eight isomers — only one of which matches natural E's chemistry, leaving the other seven with limited bioactivity at roughly half the potency. Natural forms are labeled "d-" or "RRR-" (as in d-alpha tocopherol), whereas synthetic forms carry the "dl-" or "all-rac-" designation. Equisoft uses the natural "d-alpha" form so the antioxidant works at full strength against the free radicals that damage skin cells and tissue.
How is Equisoft applied, and how little do you really need? Because the cream is so concentrated, the directions emphasize restraint: apply lightly, in thin layers, rather than slathering it on. On Rubicon, volunteers applied it three times daily to the burned skin; for routine human use the guidance is a light application about twice daily as an evening moisturizer on face, neck, under-eyes, feet and any area needing deep moisture. The same jar works on equine wounds, scrapes, dry coats and scurf, and on dogs and cats, making it a single-product alternative to keeping multiple specialty creams on hand.
What results do owners report, and how do you buy it? Testimonials run from the dramatic — M. Wendle wrote that after applying Equisoft to open wounds, "The Next DAY they were almost completely healed," and the site documents Puzzler the Pony's burn recovery from 9/7/2020 to 10/7/2020 — to everyday skin wins, like Marty M of Portland, OR reporting that lifelong eczema improved more than anything else she'd tried. Order directly from the online store at equisoftcream.com (Equisoft Original $26.00, Equisoft Natural $29.00), where the lineup also includes an organic Vitamin E & Coffee bar soap ($10.00), a Vitamin E lip balm ($8.00), and a Personal Spa Package. Questions go to (888) 708-3303.
Equisoft is a rich skin cream built around natural Vitamin E, available in an Original and a plant-based Natural formula. It was first developed by an equine rescue to heal a severely burned horse named Rubicon and is now used on horses and people alike.
How much Vitamin E does Equisoft contain?
Both the Original and Natural formulas contain natural Vitamin E (d-alpha tocopheryl acetate) at 25 percent, which works out to roughly 30,000 I.U. per jar.
What is the Original formula made with?
The Original cream combines 25 percent natural Vitamin E with purified water, glycerol stearate, isopropyl myristate, stearic acid, sorbitol, decyl oleate, cetyl alcohol, allantoin, and other conditioning agents to create a deeply moisturizing base.
How is the Natural formula different?
The Natural formula keeps the same 25 percent Vitamin E (sourced from sunflower oil) and leans on plant-derived ingredients such as evening primrose, arginine, lavender oil, orange oil, grapefruit seed extract, and rosemary extract for those who prefer a more botanical blend.
What can Equisoft Cream be used for?
Owners use Equisoft on a variety of skin challenges, including wounds, scars, scratches, and dry or cracked skin. It can be applied to the face, neck, feet, and any other area that needs deep moisturizing.
How do you apply Equisoft Cream?
Apply a small amount to the area in need and work it into the skin. The makers recommend frequent light application rather than heavy amounts, because the formula is concentrated and a little goes a long way.
Who is the horse behind the brand?
The brand is named for the burned horse, Rubicon, that the formula was created to save. After volunteers applied the cream three times daily, his scars softened, new hair grew back, and within two years his coat had fully regrown across his spine, sides, and head.
Is Equisoft only for horses?
No. The volunteers who developed the cream found it worked just as well on their own skin, which is why Equisoft is now made for both people and pets, with proceeds supporting equine rescue.
What is Equisoft Cream used for on horses?
Equisoft is a vitamin E-based skin cream used on horses for burns, open wounds, scrapes, scarring, dry or scurfy coats, and general skin conditioning. It was originally formulated to heal Rubicon, a severely burned rescue horse, after prescription medications and plain Vitamin E oil failed. Volunteers applied it three times daily and over two years his first- and second-degree burns healed completely with full, healthy hair regrowth.
What is in Equisoft Cream?
Both versions are built around 30,000 IUs of pure natural Vitamin E (d-alpha Tocopheryl Acetate from sunflowers), about 25% by volume. Equisoft Original adds purified water, glycerol stearate, isopropyl myristate, stearic acid, allantoin, decyl oleate and cetyl alcohol. Equisoft Natural drops the mineral oils and artificial fragrance/colors and instead uses evening primrose oil, arginine, lavender oil, orange oil, grapefruit seed extract and rosemary extract with a natural potassium-sorbate preservative.
How much does Equisoft Cream cost?
Equisoft Original is $26.00 and Equisoft Natural is $29.00, ordered directly from equisoftcream.com. The brand also offers an organic Vitamin E & Coffee bar soap for $10.00, a Vitamin E lip balm for $8.00, and a Personal Spa Package bundle.
What is the difference between Equisoft Original and Equisoft Natural?
Both contain the same 30,000 IU dose of natural Vitamin E. Original uses a conventional emollient base (including mineral oil and a standard preservative system) for $26.00. Natural, at $29.00, contains no mineral oils, artificial colors or artificial fragrance, is fortified with evening primrose oil, and uses a natural preservative system, making it the botanical alternative.
Can Equisoft Cream be used on people, not just horses?
Yes. Although it was created to heal a burned horse, volunteers who applied it to Rubicon noticed their own skin improving, which led the company to market it for people, cats and dogs as well. Human users apply it to face, neck, under-eyes, feet and body, and report help with chapped lips, eczema, splitting and very dry skin.
Who makes Equisoft Cream and where is it based?
Equisoft is made in Sonoma County, California, and operates from 122 Calistoga Rd Ste 232, Santa Rosa, CA 95409. The company can be reached at (888) 708-3303 and orders are placed through the online store at equisoftcream.com.
Is Equisoft Cream made in the USA?
Yes. Equisoft states its products are made with the highest-quality 100% USA ingredients, including medical-grade, natural-source Vitamin E. The cream is produced in Sonoma County, California.
Why does Equisoft use natural Vitamin E instead of synthetic?
Natural Vitamin E contains a single isomer the body uses fully, while synthetic Vitamin E creates eight isomers — only one of which matches natural E's chemistry, leaving the other seven with limited bioactivity at about half the potency. Natural forms are labeled d- or RRR- (such as d-alpha tocopherol), and synthetic forms are labeled dl- or all-rac-. Equisoft uses the natural d-alpha form for maximum antioxidant strength.
Does buying Equisoft Cream support horse rescue?
Yes. The product was created by an equine rescue and a portion of every sale funds horse-rescue work. The company deliberately commercialized the cream as a sustainable way to fund the rehabilitation of rescued animals, so each jar helps support that mission.
Who was Rubicon and why does the brand mention him?
Rubicon was a severely burned horse taken in by an equine rescue. After three months of intensive care his health had recovered everywhere except his skin, where the burns refused to heal despite prescription medications, plain Vitamin E oil and costly imported preparations. The newly discovered Equisoft formula, applied three times daily, softened the burns within weeks, regrew fuzzy new hair within two months, and left almost no scarring after a year — which is why the brand carries his story.
Is Equisoft Cream greasy?
No. Equisoft is formulated to be non-greasy and to absorb smoothly, leaving skin feeling soft and radiant. Because it is highly concentrated, only a thin layer is needed, which helps avoid a heavy or oily feel.
Can I use Equisoft Cream on dogs and cats?
Yes. Equisoft is marketed for people, cats, dogs and horses, and is used on pets for dry skin, wounds and skin irritation. The same jar can serve the whole household, which the company positions as a single-product alternative to keeping multiple specialty creams.
How fast does Equisoft Cream work on wounds?
Results vary, but testimonials report fast improvement: customer M. Wendle wrote that after applying Equisoft to open wounds, they were almost completely healed the next day. On burns, visible softening appeared within weeks for Rubicon, with fuzzy new hair growing back after about two months and near-complete healing over a year of consistent use.
How much Vitamin E is in Equisoft Cream?
Each jar of both Equisoft Original and Equisoft Natural contains 30,000 IUs of pure natural Vitamin E, which works out to roughly 25% Vitamin E by volume — a notably high concentration for a topical cream.
Does Equisoft offer products besides the cream?
Yes. Beyond Equisoft Original ($26.00) and Equisoft Natural ($29.00), the store carries an organic Vitamin E & Coffee bar soap ($10.00) that takes about eight weeks to cure per bar, a natural Vitamin E lip balm ($8.00), and a discounted Personal Spa Package bundle.
How do I order Equisoft Cream or ask a question?
Order directly from the online store at equisoftcream.com, where Equisoft Original is $26.00 and Equisoft Natural is $29.00. For questions, call (888) 708-3303 or write to Equisoft Cream, 122 Calistoga Rd Ste 232, Santa Rosa, CA 95409.