Protect Your Horse's Skin And Coat

Pro-Tect Anti Microbial Shampoo is a gentle, deep penetrating, therapeutic formula that goes beyond

Got a horse with skin infections and need a deep antimicrobial shampoo to eliminate them?

Reviewed by Ann Pruitt, InfoHorse.com · Updated June 2026

Mane 'n Tail Pro-Tect Antimicrobial Medicated Shampoo 32 oz bottle front by Straight Arrow

Protect Your Horse's Skin And Coat

Pro-Tect Anti Microbial Shampoo by Straight Arrow
Pro-Tect Anti Microbial Shampoo is a gentle, deep penetrating, therapeutic formula that goes beyond other antifungal and antibacterial products to eliminate harmful organisms.

Protect Your Horse's Skin And Coat

Harmful bacteria can thrive on your horse's skin and coat. Regular shampooing is not enough to remove these harmful bacteria. The Pro-Tect line provides complete broad-spectrum protection and treatment that eliminates harmful organisms with proven results for faster healing. Pro-Tect Shampoo is a gentle, water based formula that is non-drying, non-flammable, non-staining with a pleasant scent.

Pro-Tect Anti Bacterial Shampoo Is The Answer!

Effective against skin problems associated with bacteria, yeast, mold, fungi and viruses

* Broad-spectrum activity protects against difficult to identify opportunistic

* Safe for shampooing animals with skin injuries including cuts, tears and abrasions

* Can be used to treat existing skin problems and also as a preventative when used regularly

* pH adjusted formula leaves skin and coat clean and conditioned

* Speeds healing

* Pleasant fragrance

* Available sizes: 32 oz., 4 oz.

Where Can I Buy Pro-Tect Anti Microbial Shampoo?
Spray-Away and other great Straight Arrow products are available
JeffersEquine, ValleyVet, DoverSaddlery, SmartPak
and at most feed and tack stores, but we are happy to get you to our dealers or to help you personally with questions via email or phone calls.

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Pro-Tect Anti Microbial Shampoo is a gentle, deep penetrating, therapeutic formula that goes beyond

What exactly is Pro-Tect Anti Microbial Shampoo?

Pro-Tect is a veterinary-strength antimicrobial medicated shampoo from the Mane 'n Tail Equine line, engineered to deliver complete cleaning and protective treatment of topical skin problems in one bottle. It is not a cosmetic wash but a therapeutic formula, sold in a 32 oz bottle (SKU 54460-E) for $16.99 directly from the maker. The companion Pro-Tect Antimicrobial Medicated Spray (SKU 54464-E, also $16.99) lets owners shampoo the whole horse and then spot-treat trouble areas between baths.

Mane 'n Tail Pro-Tect Medicated Shampoo 32 oz back label with directions by Straight Arrow

Who makes it, and what is the company behind the bottle?
Pro-Tect is manufactured by Straight Arrow Products, Inc., the family-owned company that has been making the legendary Mane 'n Tail line for more than 50 years under the motto "Serving our Customers with Tradition, Technology and Trust." The same company produces Mane 'n Tail Original Shampoo and Conditioner, Cowboy Magic, Exhibitor's show-coat products, and the Straight Arrow Therapeutic line. Consumer questions go to, and the Mane 'n Tail Equine team can be reached at weekdays 9am-4pm EST.

Mane 'n Tail Pro-Tect Antimicrobial Medicated Spray 32 oz bottle front by Straight Arrow

What is the active ingredient and how does it work?

The therapeutic power comes from an exclusive Quatracin Benzalkonium Chloride base, a broad-spectrum antimicrobial agent. Rather than targeting just one type of organism, the formula works against bacteria, yeast, mold, fungi, and viruses associated with common equine skin conditions. The pH-balanced base is gentle enough to be safe for daily use, yet strong enough to be classified as veterinary strength, leaving the skin and coat clean and conditioned with a pleasant fragrance after rinsing.

Mane 'n Tail Pro-Tect Medicated Spray 32 oz back label by Straight Arrow

Which skin problems does it actually treat?

Pro-Tect is commonly used on rain rot, scurf, ringworm, scratches, hot spots, dry patches, girth itch, and general skin rashes. Because regular shampooing alone is not enough to remove the harmful organisms that thrive on a horse's skin and coat, the medicated formula goes after the cause rather than just rinsing the surface. The gentle base is formulated to be safe even on existing skin injuries such as cuts, tears, and abrasions, making it usable on horses, pets, and livestock.

How do you use it for best results?

For the shampoo, apply directly to the skin and coat and massage thoroughly over the entire body for roughly 7 minutes, then allow the lather to sit for a full 10 minutes of contact time before rinsing well. (A common bucket-dilution method is 2-4 ounces of shampoo per gallon of water applied with a sponge, with the same 10-minute dwell time.) It can be used as needed until the condition improves, typically about once weekly, and then maintained as a preventative when used regularly through wet or muddy seasons.

Where can you buy it and at what price?

Pro-Tect Antimicrobial Medicated Shampoo (32 oz) sells for $16.99 and the matching Spray for $16.99 directly at manentailequine.com; a Shampoo + Spray 2-Pack is offered for $25.99, saving money over buying the two separately. It is also widely stocked through tack, farm, and animal-health retailers nationwide. Because it is made in the USA by Straight Arrow Products, Inc. and carries the Mane 'n Tail name, buyers can find it almost anywhere quality horse grooming supplies are sold.

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The Solution Section (FAQ)

Why isn't regular shampooing enough for my horse's skin?

Harmful bacteria can thrive on your horse's skin and coat, and regular shampooing is not enough to remove them. The Pro-Tect line provides complete broad-spectrum protection and treatment that eliminates harmful organisms with proven results for faster healing.

What skin problems is Pro-Tect Anti Microbial Shampoo effective against?

Pro-Tect is effective against skin problems associated with bacteria, yeast, mold, fungi and viruses. Its broad-spectrum activity also protects against difficult-to-identify opportunistic organisms, and it can be used both to treat existing skin problems and as a preventative when used regularly.

Is Pro-Tect gentle enough to use on a horse with cuts or abrasions?

Yes. Pro-Tect Shampoo is a gentle, water-based formula that is non-drying, non-flammable, and non-staining with a pleasant scent. It is safe for shampooing animals with skin injuries including cuts, tears and abrasions, and its pH-adjusted formula leaves skin and coat clean and conditioned while speeding healing.

What sizes does Pro-Tect Anti Microbial Shampoo come in?

Pro-Tect Anti Microbial Shampoo, by Straight Arrow, is available in 32 oz. and 4 oz. sizes.

What is Pro-Tect Anti Microbial Shampoo used for?

Pro-Tect is a veterinary-strength antimicrobial medicated shampoo used to clean and treat topical skin problems on horses. It is commonly used on rain rot, scurf, ringworm, scratches, hot spots, dry patches, girth itch, and general skin rashes. It both treats existing problems and, used regularly, acts as a preventative against the organisms that cause them.

Who makes Pro-Tect Anti Microbial Shampoo?

It is made by Straight Arrow Products, Inc., the family-owned company behind the Mane 'n Tail brand. Straight Arrow has been producing grooming and therapeutic solutions for over 50 years under the motto 'Serving our Customers with Tradition, Technology and Trust,' and it is part of the Mane 'n Tail Equine line. The product is made in the USA.

What is the active ingredient in Pro-Tect Shampoo?

The active therapeutic ingredient is an exclusive Quatracin Benzalkonium Chloride base. Benzalkonium chloride is a broad-spectrum antimicrobial that targets bacteria, yeast, mold, fungi, and viruses. This is what allows Pro-Tect to go beyond ordinary antifungal or antibacterial washes and attack a wide range of harmful skin organisms.

How do you use Pro-Tect Antimicrobial Medicated Shampoo on a horse?

Apply the shampoo directly to the skin and coat and massage thoroughly over the entire body for about 7 minutes, then allow the lather to remain in contact with the skin for a full 10 minutes before rinsing well. A common bucket method uses 2-4 ounces of shampoo per gallon of water, applied with a sponge and worked into a lather. The 10-minute dwell time gives the antimicrobial base time to work.

How often should I use Pro-Tect Shampoo?

It can be used as needed, typically about once weekly, until the skin condition improves. Because the pH-balanced formula is safe for daily use, it can also be used more frequently during active outbreaks. Once the problem clears, regular use serves as ongoing prevention, especially through wet or muddy seasons when rain rot and scratches are most common.

Is Pro-Tect safe to use on cuts, wounds, or injured skin?

Yes. The gentle, pH-balanced formula is specifically designed to be safe for use on horses with existing skin injuries such as cuts, tears, and abrasions. It provides gentle skin and wound cleaning with broad-spectrum effectiveness for faster healing, which is why it is grouped in the Mane 'n Tail Equine first-aid category.

What skin conditions does Pro-Tect treat?

Pro-Tect is commonly used on rain rot, scurf, ringworm, scratches, hot spots, dry patches, girth itch, and skin rashes. It is effective against skin problems associated with bacteria, yeast, mold, fungi, and viruses. It works as both a treatment for active conditions and a preventative when used regularly.

How much does Pro-Tect Antimicrobial Medicated Shampoo cost?

The 32 oz Pro-Tect Antimicrobial Medicated Shampoo (SKU 54460-E) sells for $16.99 directly from manentailequine.com. The matching Pro-Tect Antimicrobial Medicated Spray is also $16.99, and a Shampoo + Spray 2-Pack is offered for $25.99. Prices may vary at third-party tack and farm retailers.

What sizes does Pro-Tect Shampoo come in?

Pro-Tect Antimicrobial Medicated Shampoo is sold in a 32 oz (one-quart) bottle. The companion Pro-Tect Antimicrobial Medicated Spray is also offered in a 32 oz size, and the two are available together as a 2-Pack bundle.

What is the difference between Pro-Tect Shampoo and Pro-Tect Spray?

Both share the same veterinary-strength antimicrobial formula and treat the same conditions (rain rot, scurf, ringworm, scratches, hot spots, rashes). The shampoo is used to wash and treat the whole horse during bathing, while the spray is designed for convenient spot-treatment of trouble areas between baths. Many owners use them together, which is why they are sold as a 2-Pack.

Can Pro-Tect be used on dogs, cats, or other livestock?

Yes. Pro-Tect Antimicrobial Medicated Shampoo and Spray are labeled for use on horses, pets, and livestock. The same broad-spectrum antimicrobial base that treats equine skin conditions works on similar bacterial and fungal skin problems in other animals.

Does Pro-Tect Shampoo treat rain rot?

Yes, rain rot is one of the most common conditions Pro-Tect is used for. Rain rot is a bacterial skin infection, and the Quatracin Benzalkonium Chloride base attacks the bacteria that cause it. For best results, lather the affected areas, let the shampoo sit for 10 minutes before rinsing, and repeat regularly until the scabs and crusty patches clear.

Is Pro-Tect Shampoo pH balanced?

Yes. Pro-Tect uses a pH-adjusted, pH-balanced formula that is safe for daily use. The balanced pH helps the medicated shampoo cleanse and treat the skin without stripping or irritating it, and a pleasant fragrance leaves the skin and coat clean and conditioned after rinsing.

Why isn't regular horse shampoo enough for skin problems?

Harmful bacteria, fungi, and other organisms can thrive on a horse's skin and coat, and regular shampooing only cleans the surface without eliminating the organisms causing the problem. Pro-Tect's antimicrobial Quatracin Benzalkonium Chloride base penetrates deeply and remains in contact with the skin for 10 minutes to kill the organisms, going beyond what an ordinary cosmetic shampoo can do.

Where can I buy Pro-Tect Anti Microbial Shampoo?

It can be purchased directly from the manufacturer at manentailequine.com, and it is widely stocked at tack shops, farm stores, and animal-health retailers nationwide such as Riding Warehouse, PBS Animal Health, Murdoch's, and CountryMax. Because it carries the well-known Mane 'n Tail name and is made in the USA, it is easy to find wherever quality horse grooming supplies are sold.

How do I contact Straight Arrow / Mane 'n Tail about Pro-Tect?

The Mane 'n Tail Equine team can be reached by phone at 610-882-9606 on weekdays from 9am to 4pm EST. Consumer questions can also be emailed to [email protected]. The company also maintains a presence on Facebook (facebook.com/StraightArrowProducts) and LinkedIn.

Is Pro-Tect Shampoo made in the USA?

Yes. Pro-Tect Antimicrobial Medicated Shampoo is manufactured in the USA by Straight Arrow Products, Inc., the family-owned maker of the Mane 'n Tail line. The brand has been producing trusted grooming and therapeutic solutions for over 50 years.