K9Transfer Factors™

Antibodies are like little soldiers that scour the body seeking and destroying damaged cells! com

Got a dog facing cancer and want transfer-factor support a grieving family discovered?

Reviewed by Ann Pruitt, InfoHorse.com · Updated June 2026

K9 Medicinals TransFactor Plus 2.5 purified colostrum immune support wafers for dogs - bottle

K9Transfer Factors™

K9 Transfer Factor™ by K9 Medicinals

Transfer Factors help create antibodies. Antibodies are like little soldiers that scour the body seeking and destroying damaged cells!

What sets K9Medicinals.com Apart From Competitors?

We are a family business, who started selling these products after our own dog was diagnosed with cancer and given two weeks to live. K9Immunity extended our dog’s life by two years. We are passionate about helping others going through this trauma and want to keep healthy dogs well so no family has to go through what we did. All of our products are made in the U.S.A. and all of the ingredients are made in the U.S.A. as well. They are formulated in FDA certified laboratories to human grade standards. They are safe, organic, natural and have no known interactions with any other supplement or medication. They are safe for even pregnant or nursing canine mothers. Some other companies advertise their products are made in the U.S.A., but the ingredients come from other countries who have no safety standards. We have a full money back guarantee and a wonderful support system for our customers and their canine family members.

K9 Transfer Factor™

Transfer factors are proteins your dog naturally produces. These proteins join with other immune-specific molecules to create antibodies. Antibodies are like little soldiers that scour the body seeking and destroying damaged cells. But when your dog has cancer, he’s can’t produce the amount of transfer factors he needs. And without enough transfer factors, he can’t create the antibodies he needs for stronger health. That’s why we created K9Transfer Factors™. Transfer factor supplements alone aren’t known to have any effect on dogs with cancer. But if your dog is taking K9 Immunity™, we Highly recommended using K9 Transfer Factor™ in conjunction.

That’s because K9 Transfer Factor™ is designed to bond with the immune-modulating compounds in K9 Immunity™. By doing so, it increases their absorption and bioavailability. This significantly enhances K9 Immunity’s™ effectiveness. In turn, it increases your dog’s chances for improvement

There are many brands of transfer factors available in health food stores. Both human grade and canine grade work with K9 Immunity™. However, our manufacturers invested over three years researching with a major veterinary nutrition company to develop the ultimate transfer factor for maximum effectiveness. And K9 Transfer Factor™ comes in an easy to chew, liver flavored wafer dogs love.

Guaranteed safe, natural and effective

Safe for all breeds and sizes
Safe to use with other cancer treatments
Made with 100% USDA Certified Organic materials
Manufactured in a FDA registered facility
100% non GMO
Created according to the highest pharmaceutical standards
Absolutely no binders, fillers, flow enhancers or time release agents
Have no known side-effects
100% non-toxic (no risk of overdosing)
Backed by our full satisfaction guarantee
Made in the USA to human grade standards

K9 Immunity™

K9 Immunity™ strengthens and balances your dog’s immune system so the body recognizes and destroys damaged cells. This improves their body’s ability to overcome illness and helps protect them against future illness.

Your dog’s immune system works in two ways:

Keeps existing cells healthy as they replicate
Rids damaged cells (like cancer cells) before they can multiply

Once your dog’s immune system strengthens, it may also help them:

Increase response to cancer treatment
Speed up recovery
Reduce side-effects from other cancer therapies
Prevent a serious future illness/relapse
Improve quality of life
Extend their time with you

K9 Immunity Plus™

K9 Immunity Plus™ is an intense immune-boosting daily supplement designed to provide maximum support for dogs with cancer. And it comes in a convenient, easy to administer form.

This formula includes all of the ingredients in our successful K9 Immunity™. Then we intensified it by adding:

Transfer Factors Increases the formula’s effectiveness and results. The immune-active polysaccharides in K9 Immunity™ work by bonding with your dog’s immune proteins. Transfer factors are needed for this bonding to occur. The added transfer factors increase the number of naturally-occurring bonds. In turn, this activates a greater number of immune cells for better results.

Omega 3 Essential Fatty Acids Omega 3 essential fatty acids are well-studied to help shrink tumors, lower inflammation and provide a host of other health benefits. Making it more pleasant for your dog, K9 Immunity Plus™ comes in easy to chew wafers with natural liver and fish flavors dogs love.

What Symptoms Should I Look For To Alert Me To A Poor Immune System?

Boosting the immune system for proper working biochemical interactions is important to your dog’s wellness. The immune system is constantly protecting the body from parasites, bacterial, fungal, or virus-infected cells. Boosting your dog’s immune system will help his body overwhelm bacteria, destroy toxins, or kill viruses. Infected cells produce interferon and other cytokines, which can signal contiguous uninfected cells to intensify their defenses, enabling them to damage invaders.

In a weak immune system, bacteria, viruses, micro organisms, and toxins can pass the immune defending cells, and generate disorders. A lowered immune system function in dogs results in acute or chronic fungi, allergies, yeast infections, eczema, demodectic mange, food allergy, arthritis, ear infections, slowly healing wounds, or fertility disorders.

What If My Dog Is Healthy, Can These Products Still Help?

YES!! Absolutely, they can help. Our goal is to help your healthy dog stay healthy and your sick dog heal and have a good quality of life and extended years with your family.

Order Transfer Factors For Your Dogs Immune Health Today!

Make sure your dog has a healthy immune system to fight off disease, infection and to help support general well being and joy in their every day lives by using products from K9Medicinals. For more information about our immunity line of products, please call us today!

What exactly is a transfer factor?

Transfer factors are tiny immune-signaling molecules the body uses to recognize and defend against harmful microbial threats. In the first days of life, a mother passes this "immune knowledge" to her newborn through colostrum — a nutrient-rich first milk packed with genetic information that teaches the immune system to tell healthy cells from abnormal ones. K9 Medicinals captures that same biology in supplement form so an adult dog's immune system can be reminded how to identify and destroy damaged cells.

K9 Medicinals K9 Immunity Plus immune support chews for dogs with added transfer factors - front of bag

Why a grieving dog family built this company

K9 Medicinals is a small, family-owned business in Reno, Nevada, run hands-on by owner Dorla. The company was born out of heartbreak: the family started selling these products after their own dog was diagnosed with cancer and given two weeks to live. That personal experience still shapes the business — Dorla answers the phone and replies to customer reviews personally, and the company says its products have now helped over a million dogs.

K9 Medicinals K9 Immunity Plus large dog bag back label with ingredients and feeding directions

Inside the colostrum that powers TransFactor Plus 2.5

The standalone TransFactor Plus 2.5 ($29.95) is a purified colostrum supplement: each bottle holds 30 wafers, and each wafer delivers 500 mg of colostrum. The colostrum is premium refined material collected during the first 16 hours after birthing from USDA Grade-A dairy cows, then processed over low heat to preserve maximum bioactivity. That gentle handling yields a finished colostrum containing a minimum of 18% immunoglobulins — the antibody-rich fraction that does the immune work.

Ohana Mushrooms K9 Immunity organic medicinal mushroom immune supplement bottle for dogs - front

How transfer factors team up with K9 Immunity

The immune-active polysaccharides in companion product K9 Immunity work by bonding with a dog's own immune proteins, and transfer factors are exactly what's needed for that bonding to occur. Adding transfer factors increases the number of naturally-occurring bonds, which in turn activates a greater number of immune cells for stronger results. This is why the manufacturer combined all three legacy products — K9 Immunity, K9 Transfer Factors, and K9 Omega — into the convenient K9 Immunity Plus wafer, which costs less than buying each separately.

Made in America, clinically tested, patent-protected

The flagship K9 Immunity formula is 100% made in America from only American ingredients — no imported Chinese material — in a certified Good Manufacturing Process (cGMP) facility. It draws over 200 immune-active heteropolysaccharides from six 100% USDA Certified Organic, Certified Kosher, non-GMO medicinal mushroom species: Agaricus blazei, Cordyceps sinensis, Grifola frondosa, Ganoderma lucidum, Coriolus (Trametes) versicolor, and Lentinula edodes. The proprietary solid-substrate fermentation process is so unusual it holds U.S. patent #8008060, and K9 Immunity says it is the only canine immune supplement with peer-reviewed published clinical trials.

How to order and the money-back promise

Every K9 Medicinals product is backed by a full money-back satisfaction guarantee — if you aren't completely satisfied, return the unused portion (even one capsule) for a full refund within 30 days. U.S. orders over $60 ship free within the 48 contiguous states plus Hawaii and Alaska, with same-day shipping on orders placed before 2:00pm PST Monday–Friday. Reach the family directly for telephone orders and customer care at (888) 366-3641 or; returns go to K9 Medicinals – Returns, 10235 Coyote Creek Drive, Reno, Nevada 89521.

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The Solution Section (FAQ)

What sets K9Medicinals.com Apart From Competitors?

We are a family business, who started selling these products after our own dog was diagnosed with cancer and given two weeks to live. K9Immunity extended our dog s life by two years. We are passionate about helping others going through this trauma and want to keep healthy dogs well so no family has to go through what we did. All of our products are made in the U.S.A. and all of the ingredients are made in the U.S.A. as well. They are formulated in FDA certified laboratories to human grade standards. They are safe, organic, natural and have no known interactions with any other supplement or medication. They are safe for even pregnant or nursing canine mothers. Some other companies advertise their products are made in the U.S.A., but the ingred

What Symptoms Should I Look For To Alert Me To A Poor Immune System?

Boosting the immune system for proper working biochemical interactions is important to your dog s wellness. The immune system is constantly protecting the body from parasites, bacterial, fungal, or virus-infected cells. Boosting your dog s immune system will help his body overwhelm bacteria, destroy toxins, or kill viruses. Infected cells produce interferon and other cytokines, which can signal contiguous uninfected cells to intensify their defenses, enabling them to damage invaders.

What If My Dog Is Healthy, Can These Products Still Help?

YES!! Absolutely, they can help. Our goal is to help your healthy dog stay healthy and your sick dog heal and have a good quality of life and extended years with your family.

What is K9 TransFactor Plus 2.5?

TransFactor Plus 2.5 is K9 Medicinals' standalone transfer-factor supplement, a purified colostrum product that encourages a healthy immune system in dogs. Each bottle contains 30 wafers, and each wafer provides 500 mg of colostrum. It sells for $29.95 on K9Medicinals.com.

What are transfer factors and how do they work?

Transfer factors are molecules the immune system uses to defend against harmful microbial threats. In the first days of life, a mother passes vital immune knowledge to her newborn through colostrum, a bioactive first milk packed with genetic information that helps the immune system tell healthy cells from abnormal ones. A supplement like TransFactor Plus 2.5 delivers those same molecules to an adult dog whose body may no longer produce enough on its own.

Where does the colostrum in TransFactor Plus 2.5 come from?

It is premium refined colostrum collected during the first 16 hours after birthing from USDA Grade-A dairy cows. K9 Medicinals processes it over low heat to preserve maximum bioactivity. The finished colostrum contains a minimum of 18% immunoglobulins, the antibody-rich fraction responsible for its immune benefits.

What is the dosage for TransFactor Plus 2.5?

The recommended dose is 1 wafer per day. Each wafer contains 500 mg of colostrum, and each bottle holds 30 wafers, giving roughly a one-month supply per bottle. As with any supplement added during conventional treatment, it's wise to confirm the plan with your veterinarian.

What kinds of issues is colostrum used to support?

K9 Medicinals notes that colostrum's healing effects cover many areas, including allergies, bacterial or viral infections, autoimmune diseases, and digestive problems. Because it works at the level of immune signaling rather than treating one symptom, it's positioned as broad daily immune support. Individual results will vary.

How do transfer factors work together with K9 Immunity?

The immune-active polysaccharides in K9 Immunity work by bonding with your dog's own immune proteins, and transfer factors are needed for that bonding to occur. Adding transfer factors increases the number of naturally-occurring bonds, which activates a greater number of immune cells for better results. That synergy is why K9 Medicinals recommends pairing transfer factors with K9 Immunity rather than using them alone.

What is the difference between K9 Transfer Factors and K9 Immunity Plus?

Historically, dogs with health issues took three separate products: K9 Immunity, K9 Transfer Factors, and K9 Omega. K9 Immunity Plus combines all three into one convenient wafer that costs less than buying each separately. So transfer factors are available either as the standalone TransFactor Plus 2.5 or already built into the all-in-one K9 Immunity Plus formula.

Who makes K9 Medicinals products?

K9 Medicinals is a small, family-owned company based in Reno, Nevada. The owner, Dorla, runs it hands-on and personally answers customer calls and reviews. The family started the business after their own dog was diagnosed with cancer and given two weeks to live, which is why their messaging emphasizes empathy with owners facing a serious diagnosis.

Are K9 Medicinals products made in the USA?

Yes. K9 Immunity and all other K9 Medicinal products are made in America using only American ingredients, with no imported Chinese ingredients. Manufacturing occurs in an FDA-certified, certified Good Manufacturing Process (cGMP) facility in accordance with the highest pharmaceutical standards, and the mushrooms are grown in a highly regulated organic facility in the U.S.

What is K9 Immunity made from?

K9 Immunity is a combination of over 200 highly purified, immune-active high-molecular-weight heteropolysaccharides and Beta 1,3-1,6 beta glucans. It is produced from six 100% USDA Certified Organic, Certified Kosher, non-GMO medicinal mushroom species: Agaricus blazei, Cordyceps sinensis, Grifola frondosa, Ganoderma lucidum, Coriolus (Trametes) versicolor, and Lentinula edodes. The company says research shows it activates all 260 different classes of immune cells, including NK cells, T-cells, and macrophages.

Is K9 Immunity patented or clinically tested?

Yes. The proprietary solid-substrate fermentation process is covered by U.S. patent #8008060, the only patent ever granted on a substrate allowing full 100% bio-conversion into biologically active immune-modulator compounds, with additional patents pending. K9 Medicinals also states that K9 Immunity is the only canine immune supplement with actual peer-reviewed published clinical trials.

Is K9 Immunity a drug?

No. K9 Medicinals describes its products as veterinary health supplements, specifically immune-system enhancements for dogs facing serious health challenges. They are not drugs and are not claimed to cure disease, though the company says they may improve quality of life and extend a dog's time with its family.

Can I give these supplements to a healthy dog?

Yes. Although the formulas are designed for dogs with health problems, K9 Medicinals recommends them as a daily supplement for healthy dogs too, much like how people take daily vitamins. The immune-boosting formula helps maintain good health and is said to reduce the risk of future illness. Individual results will vary.

Are these products safe for dogs already undergoing conventional treatment?

K9 Medicinals says its products are safe alongside conventional therapy and often increase the effectiveness of other treatments. The company advises discussing any supplement with your veterinarian or oncologist first, as you would with any herb or supplement during conventional care.

Can cats take these products too?

Yes. K9 Medicinals states all of its pet products are equally effective on cats, because a dog's and a cat's body systems are essentially the same. The company reports hearing great success stories from cat owners as well.

What is the satisfaction guarantee and return policy?

Every K9 Medicinals product carries a full money-back satisfaction guarantee. If you aren't completely satisfied, you can return the unused portion within 30 days of purchase, even if only one capsule is left, for a full refund. Returns go to K9 Medicinals – RETURNS, 10235 Coyote Creek Drive, Reno, Nevada 89521, with your name, phone number, and mailing address enclosed; refunds typically post within 5 to 7 business days.

How much is shipping and how do I order?

Shipping is free on U.S. orders over $60 within the 48 contiguous states, Hawaii, and Alaska; orders under $60 pay carrier rates. Orders placed before 2:00pm PST Monday through Friday ship the same day via USPS and usually arrive within 3 to 4 days. To order or ask questions, call the family-run care line at (888) 366-3641 or email [email protected]; note the company no longer ships internationally.