Wire2Wire Vet Products

SilvaPlex® products are unlike anything else on the market, due to their PATENTED "Next Generation"

Got a stubborn dog issue and want patented silver technology from two veterinarians?

Reviewed by Ann Pruitt, InfoHorse.com · Updated June 2026

SilvaPlex Ag21 Chelated Silver Pet Shampoo bottle for dogs and horses

Wire2Wire Vet Products

Wire2Wire Vet Products by Dr. Michael Cavey D.V.M.
SilvaPlex®products are unlike anything else on the market, due to their Patented "Next Generation" Silver Technology!

About Wire 2 Wire Vet Products- 2 Veterinarians Improving Horse Health!

Wire 2 Wire Vet Products, LLC was started in 2005 byMichael Cavey, DVM, and his wifeNancy Temple DVM , married in 1994, dedicated horse owners and equestrians. Together they operate "Respite Farm, Inc", as a successful Thoroughbred breeding and racing operation breeding Eclipse Award winning ChampionsUncle MoandChampagne Room; they have been regular consignors to the major breeding sales in Kentucky.

Michael and Nancy’s goal to develop unique products to improve animal health care- especially within the equine world has become a reality, with their one-of-a-kind, flagship product“SilvaPlex®” and other related superior products.

Joining these amazing Husband/Wife Veterinarians isRichard Hoffberger, an avid horseman, and the owner of an influencial equine insurance agency. Together— this unique and extremely talented team have created a line of products second to none in the horse world… and, yes, these products help dogs, cats, goats and other farm animals also!

**Introducing the One— the Only— SilvaPlex®!

Wire2Wire Vet Products, LLC is the exclusive distribution agent forSilvaPlex®products, manufactured in the USA… and it’s true— SilvaPlex®is ONE OF A Kind! The experience of our manufacturer in the areas of animal and personal care and environmental cleaning is both traditional and visionary.All Silvaplex products are manufactured from natural biodegradable raw materials that have been Ecocert-approved.

It’s the Patented next generation Chitosan Silver and patentedComplexAg21™that makes the difference in ourSilvaplex® products. TheSilvaplex® product Chief Chemist along with his collaborators, have been formulating personal care products and environmental cleaners since 1987. They also have great concern about Mother Earth and her importance in our life. Their experience and innovative ideas have been the key to our success.

SilvaPlex**® is asafer, more effectiveproduct in a category that has remained stagnant for far too long. Animal and medical professionals prefer to use products that arenaturally derived, non-toxic and child safe.SilvaPlex® is the one product containing all the ingredients to match these desired properties.

What Makes SilvaPlex® Products So Unique?

SilvaPlex® products are unlike anything else on the market thanks to their patented next-generation silver technology. Each formula is powered by:

Chitosan Silver – Known for its antimicrobial, antifungal, and wound-healing properties
ComplexAg21™ – A patented silver-based compound with superior bioavailability
Natural Biodegradable Ingredients – Ecocert-approved and gentle on animals and the environment
Alcohol-Free, Non-Toxic Formulas – Safe for use around children, pets, and sensitive animals

You won’t find harsh chemicals or outdated ingredients in SilvaPlex®. This is truly the next generation of animal health care.

Looking For Effective Help For Ringworm, Wounds Or Skin Ailments?

We get it! There is so much out there to choose from. But when it comes to the health and well being of your horses, farm animals and indoor pets, you just can’t afford to get it wrong. That is why SilvaPlex is there— to make sure youget it Right— the First time!

SilvaPlex® Wound Spray – For Everyday Skin and Wound Protection-- and highly effective for Ringworm.It’s a fast-acting, alcohol-free antiseptic you can spray directly onto wounds without worry. Because it contains patented Chitosan Silver and ComplexAg21™, it helps prevent infection while soothing and supporting natural healing. Horse owners love that it doesn’t sting—and so do their horses!

This ready-to-use spray is ideal for treating:

Cuts, scrapes, and abrasions
Rain rot or skin fungus
Insect bites
Minor hoof issues

SilvaPlex® Wound Gel –When You Need Long-Lasting Contact on Wounds or Hoovesour “Gel" version clings to the application site, making it perfect for:

Deeper or chronic wounds
Skin ulcers or proud flesh
Under wraps or hoof boots for deep-tissue support

It forms a protective barrier over the area while delivering advanced silver-based antimicrobial protection. If your horse needs extra healing power or if you’re managing a wound that rubs or stretches, this gel is a must-have.

Our SilvaPlex® Shampoo – A Healing Wash for Sensitive or Irritated Skin!This is no ordinary horse shampoo. SilvaPlex® Shampoo is formulated with gentle, naturally derived ingredients and patented silver technology to:

Clean and disinfect
Calm irritated skin
Help reduce fungal or bacterial growth
Restore coat shine and softness

Also-- Ideal for horses with:

Sweet itch
Skin infections or rashes
Post-grooming sensitivity
Rain rot or cannon crud

It’s safe for frequent use and rinses clean without harsh residues. A great product to keep in your grooming kit year-round!

Is SilvaPlex® Safe to Use Every Day?

Yes! All SilvaPlex®formulas are designed with daily-use safety in mind. There are no harsh detergents, no alcohol, and no ingredients that will damage tissue. They’re:

Child-Safe
Pet-Safe
Vet-Approved
Biodegradable and Eco-Friendly

And because they’re made in an FDA-inspected, GMP-approved facility in the USA, you can rest easy knowing quality control is held to the highest standard!

What Do Horse Owners SAY About SilvaPlex® For Their Horses?

"I have long been a fan of SilvaPlex Wound Gel. I put this stuff on everything, including cuts & scrapes on my horse and cat. I even use it on myself for scrapes, chapped lips and hands. It also helps with itching from bug bites.

A few weeks ago, we had 10 days of rain and my horse developed a skin condition with a lot of scabs as a result. I got a bottle of Silverworks Shampoo and Conditioner to try. Since it is made by the same company that makes the Wound Gel, I was more than willing to give it a try. The first time I used it on the scabs, I started spot treating a few areas, but it was a nice day, so I gave my horse a complete bath. I was impressed that even after scrubbing the scabs, it was obvious the shampoo was not burning her skin. After rinsing the shampoo off, her tail required very little brushing to be tangle free.

The next day, there were definitely less scabs. I was extremely surprised how soft and shiny it left her coat and tail. I continued to spot treat a few areas on her hind legs with great results.Thanks for making products that actually work!"

Wendy Miller

The veterinarians and grooming staff at our hospital have extensively used SilvaPlex No-Rinse Shampoo. Everyone loves this product! The groomers say that it cleans and deodorizes extremely well. Also it leaves the hair much softer. Our veterinarians use it for medicinal cleaning. They especially like the anti-microbial properties of the silver. This is a great product!

John C. Harroff D.V.M.

We used the SilvaPlex Shampoo for our 6-month-old havanese and absolutely loved it! The soap was gentle, lathered really well and washed off easily. Our pup now looks the cleanest he has ever looked. After his bath when we took him for a walk a group of people asked if he was a show dog!

Havanese Puppy

Give Your Dog the True Healing Power SilvaPlex® Offers!

Whether your Dog needs help with Ringworm or is recovering from a skin infection, or needs serious wound care—SilvaPlex® gives you a smarter, safer way to help them heal.OurSilvaPlex ®line is trusted by veterinarians, groomers, and owners who can’t afford to get it wrong, but need a trusted source for real results! Safe, Effected, Backed by Science and made with a sincere Love for the animals YOU love. Visit www.w2wvp.com Today- and discover the SilvaPlex® difference!

What is SilvaPlex and what makes its silver different?

SilvaPlex® is a veterinarian-formulated line of topical and grooming products built on Complex Ag21™, a patented chelated-silver technology that bonds silver to citric acid in a stable coordination complex. Unlike colloidal or ionic silver suspensions that can be unpredictable, this covalent bonding keeps the silver evenly distributed and active so it attaches to the skin and wound surface "like a magnet" to form a protective antimicrobial layer. A natural chitosan polymer, derived from mushrooms, works in tandem with the silver to guard against environmental stressors. The result is a Next Generation Silver Technology engineered to be non-toxic and non-stinging.

SilvaPlex Pet Shampoo benefits chart for skin and coat health

Who founded Wire 2 Wire Vet Products?

Wire 2 Wire Vet Products, LLC was started in 2005 by Michael Cavey, DVM, and his wife Nancy Temple, DVM. Dr. Cavey, a graduate of the College of William and Mary and the University of Georgia College of Veterinary Medicine, ran an equine practice for decades and built Respite Farm into a premier Thoroughbred breeding and racing operation in Kentucky, breeding Eclipse Award champions including Uncle Mo and Champagne Room. Dr. Temple, an equine surgeon trained at the University of Illinois College of Veterinary Medicine with a residency at the Marion duPont Equine Hospital, manages Respite Farm and the Wire2Wire operation and is a champion Australian Shepherd handler. Their guiding principle is simple: "we only sell products we use on our own animals."

Dog being bathed with SilvaPlex chelated silver shampoo

How does the Ag21 Pet Shampoo care for dogs and cats?

The SilvaPlex Ag21 Chelated Silver Pet Shampoo is pH-balanced specifically for the skin of dogs, cats, horses, and show cattle, deep-cleaning while preserving the natural oils that keep a coat vibrant. Its ingredient list reads Purified Water, Patented Ag21™ Chitosan Silver Complex, Aloe Vera, Vitamin E, Sweet Orange & Vanilla Oil, Vegan Glycerin, and pH-balanced Cleansers — and it is free from Harsh Sulfates, Parabens, and Artificial Dyes. The 16 oz. bottle carries a regular price of $21.95, with case packs and gallon sizes available for kennels and groomers. For pets who cannot be submerged in water, the brand also offers a SilvaPlex® No-Rinse Foam Shampoo safe for rabbits, chinchillas, guinea pigs, hamsters, and ferrets.

SilvaPlex Original Wound Gel 4 oz jar with chelated silver formula

What does the SilvaPlex Wound Gel and Wound Spray treat?

SilvaPlex Original Wound Gel is formulated for minor cuts, burns, abrasions, and ulcerations, supporting fast, effective healing and skin regeneration while helping reduce scarring. The directions are straightforward: clean the affected area, apply a generous amount directly to the wound, leave it uncovered or bandage it, and reapply one to three times daily as needed. It is safe for daily use on dogs, cats, horses, and livestock. The 4 oz. gel carries a regular price of $21.50, with 1 lb and case-of-12 options for barns and clinics.

How is the 100 PPM Chelated Silver immune-support solution used?

SilvaPlex 100 PPM Chelated Silver is a professional-grade immune-wellness solution containing only two ingredients — Patented Ag21™ Chelated Silver and pharmaceutical-grade distilled water — at a 100 PPM concentration, far stronger than typical retail solutions at 10 to 15 PPM. Wire2Wire provides a dilution guide: undiluted 100 PPM for intensive support, a 1:1 dilution to 50 PPM for large-animal maintenance, and a 1:3 dilution to 25 PPM for smaller companion pets. The 8 oz. solution carries a regular price of $31.95, and the company recommends working with a veterinarian on specific protocols.

Where are SilvaPlex products made and how do you order?

SilvaPlex is manufactured by AG Essence in Sandston, Virginia, in an FDA-inspected, GMP-compliant facility under Chief Chemist Bill Wingfield, and products ship from Respite Farm at 1040 Hume-Bedford Road, Paris, Kentucky 40361. The full line is available directly at wire2wirevetproducts.com, where the SilvaPlex collection covers wound, skin, hoof, grooming, and immune-support products for horses, cattle, dogs, and cats. To reach the company, call (859) 953-1574 or. Wire2Wire is also an authorized reseller of the Flexineb® portable equine nebulizer.

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The Solution Section (FAQ)

What makes Wire2Wire Vet Products different from other options?

SilvaPlex products are unlike anything else on the market, due to their PATENTED Next Generation Silver Technology! Wire 2 Wire Vet Products , LLC was started in 2005 by Michael Cavey, DVM , and his wife Nancy Temple DVM , married in 1994, dedicated horse owners and equestrians.

How does Wire2Wire Vet Products help horses or owners?

Because it contains patented Chitosan Silver and ComplexAg21 , it helps prevent infection while soothing and supporting natural healing. Is SilvaPlex Safe to Use Every Day? All SilvaPlex formulas are designed with daily-use safety in mind .

How do you use Wire2Wire Vet Products?

Animal and medical professionals prefer to use products that are naturally derived, non-toxic and child safe. SilvaPlex products are unlike anything else on the market thanks to their patented next-generation silver technology .

How did Wire2Wire Vet Products get started?

Wire 2 Wire Vet Products , LLC was started in 2005 by Michael Cavey, DVM , and his wife Nancy Temple DVM , married in 1994, dedicated horse owners and equestrians.

What is SilvaPlex?

SilvaPlex® is a veterinarian-formulated line of topical and grooming products from Wire2Wire Vet Products, built on COMPLEX Ag21™, a patented chelated-silver technology. The line includes wound gels and sprays, pet shampoos, a throat spray, and a 100 PPM chelated-silver immune-support solution. Products are designed for horses, cattle, dogs, and cats and are marketed for immune support, wound care, and skin care.

Who makes SilvaPlex and Wire2Wire Vet Products?

Wire 2 Wire Vet Products, LLC was started in 2005 by Michael Cavey, DVM, and his wife Nancy Temple, DVM. Both are veterinarians who run Respite Farm, a Thoroughbred breeding and racing operation in Paris, Kentucky. Their founding principle is that they only sell products they use on their own animals.

What is Ag21 Chelated Silver and how is it different from colloidal silver?

COMPLEX Ag21™ is a patented chelated-silver technology in which silver is bonded to citric acid in a stable coordination complex through covalent bonding. According to the company, this makes it more effective and predictable than colloidal or ionic silver, which can be unstable suspensions. The chelated complex stays evenly distributed and attaches to the wound or skin surface to form a protective antimicrobial layer.

Is SilvaPlex safe for my dog or cat?

Wire2Wire states that SilvaPlex is engineered to be non-toxic and non-stinging and is made with naturally derived ingredients. The products are formulated for daily use on dogs, cats, horses, and livestock. As with any new product, it is wise to consult your veterinarian, especially for the more concentrated immune-support solution.

What is in the SilvaPlex Ag21 Pet Shampoo?

The Ag21 Pet Shampoo ingredient list is Purified Water, Patented Ag21™ Chitosan Silver Complex, Aloe Vera, Vitamin E, Sweet Orange & Vanilla Oil, Vegan Glycerin, and pH-balanced Cleansers. It is free from Harsh Sulfates, Parabens, and Artificial Dyes. The formula is pH-balanced specifically for the skin of dogs, cats, horses, and show cattle.

How much does the SilvaPlex Pet Shampoo cost?

The SilvaPlex Ag21 Chelated Silver Pet Shampoo has a regular price of $21.95 for the 16 oz. bottle. Larger options include 32 oz., a 1 gallon size, and case packs (16 oz. case of 12, 32 oz. case of 4, and 1 gallon case of 2) for kennels, groomers, and barns. Prices are listed at wire2wirevetproducts.com.

Is there a no-rinse shampoo option for pets who hate baths?

Yes. SilvaPlex® offers a No-Rinse Foam Shampoo featuring the patented Ag21™ Chelated Silver Complex that delivers a quick, professional-quality grooming in minutes. It is positioned as a safe grooming option for dogs, cats, anxious animals, and small pets such as rabbits, chinchillas, guinea pigs, hamsters, and ferrets that should not be submerged in water. A 5 oz. waterless option has been offered around $10.57 to $11.75.

What does the SilvaPlex Wound Gel treat?

SilvaPlex Original Wound Gel is formulated for minor cuts, burns, abrasions, and ulcerations, and it supports fast, effective healing and skin regeneration while helping reduce scarring. It is safe for daily use on dogs, cats, horses, and livestock. The gel uses the COMPLEX Ag21™ Chelated Silver Formula.

How do I apply the SilvaPlex Wound Gel?

Clean the affected area thoroughly, then apply a generous amount of gel directly to the wound. You can leave it uncovered or apply it under a sterile bandage. Reapply one to three times daily as needed.

How much does the SilvaPlex Original Wound Gel cost?

The SilvaPlex Original Wound Gel carries a regular price of $21.50 for the 4 oz. size. It is also available in a 1 lb size and in cases of 12 (4 oz and 16 oz) for barns and clinics. Current pricing is on wire2wirevetproducts.com.

What is the 100 PPM Chelated Silver immune-support solution?

SilvaPlex 100 PPM Chelated Silver is a professional-grade immune-wellness solution containing only two ingredients: Patented Ag21™ Chelated Silver and pharmaceutical-grade distilled water. At 100 parts per million it is far more concentrated than typical retail silver solutions, which are often 10 to 15 PPM. It is marketed to support overall wellness and comfort for horses, livestock, cats, and dogs facing environmental or seasonal stress.

How is the 100 PPM solution diluted?

Wire2Wire provides a dilution guide: use it undiluted at 100 PPM for intensive support, a 1:1 dilution with distilled water to 50 PPM for large-animal maintenance, and a 1:3 dilution to 25 PPM for smaller companion pets. The company recommends consulting a veterinarian for specific protocols. The 8 oz. solution has a regular price of $31.95.

What is chitosan and why is it in SilvaPlex?

Chitosan is a natural polymer that Wire2Wire derives from mushrooms. In SilvaPlex it works in tandem with the silver to help the product adhere to the skin and protect against environmental stressors. It is part of what the company calls its advanced Chitosan compound.

Where are SilvaPlex products manufactured?

SilvaPlex products are manufactured by AG Essence in Sandston, Virginia, in an FDA-inspected, GMP-compliant facility under Chief Chemist Bill Wingfield, who has overseen production since 1987. Finished products then ship from Respite Farm in Kentucky. The company emphasizes pharmaceutical-grade, made-in-the-USA production.

Where does Wire2Wire ship from and how do I contact them?

Products ship from Respite Farm at 1040 Hume-Bedford Road, Paris, Kentucky 40361. You can reach Wire2Wire Vet Products by phone at (859) 953-1574 or by email at [email protected]. The full SilvaPlex line is available to order at wire2wirevetproducts.com.

Does Wire2Wire sell anything besides SilvaPlex?

Yes. Wire2Wire Vet Products is an authorized reseller of the Flexineb® portable equine nebulizer (made by Nortev) for delivering treatments to horses, and it has offered the Endo-Lite/The Beamer portable endoscope light source. Its core focus, however, is the SilvaPlex® chelated-silver product line for horses, cattle, dogs, and cats.

Is silver actually effective for animal skin and wound care?

Silver has a long history of use in medicine, and Wire2Wire notes it has been studied against antibiotic-resistant bacterial strains. SilvaPlex aims to provide a moist, antimicrobial wound environment that supports healing while remaining non-toxic and non-stinging. As always, serious or deep wounds and persistent skin conditions should be evaluated by a veterinarian.