Most equine supplements treat one symptom at a time. Karbo Combo+ by Gomer's Inc. takes a different starting point: the immune system itself. Built on the principle that roughly eighty percent of a horse's immune response is organized in the gut, Karbo Combo+ feeds that system directly, so the everyday bacterial, viral, fungal and environmental challenges a horse meets have a much harder time taking hold.
The result is a horse that simply functions better. When the immune system is working the way it should, clinical problems become the exception rather than the routine, and the horse carries more bloom, more resilience and more steadiness through stress. Karbo Combo+ is the signature formula in the Gomer's Inc. line, combining the active ingredients of Karbo Pellets+ with Epic II CL in one daily feeding.
Karbo Combo+ is a natural, top-dress feed supplement that delivers a dense, living culture of beneficial microorganisms alongside the building blocks the immune system needs. Each ounce supplies a minimum of 525 million CFU of probiotics, including Saccharomyces cerevisiae, Bacillus licheniformis and subtilis, several Lactobacillus strains, Bifidobacterium animalis and Enterococcus cultures.
Those probiotics work alongside the Karbo signature components: mannan and glucan sugars rich in oligosaccharides, multiple saponins, antioxidants, glycoproteins, encapsulated natural vitamins, amino acids and enzymes. The formula also carries six to eight percent organic calcium, zinc and selenium, and high levels of perna that support joint function and healing. Just as importantly, Karbo Combo+ contains no drugs, no antibiotics and no steroids.
Because it strengthens the body's own defenses rather than targeting a single pathogen, Karbo Combo+ has long been used as a partner to conventional EPM care. According to Gomer's Inc., it complements the effectiveness of Marquis during treatment, and when a horse is held on a maintenance dose afterward, the protozoa behind EPM are no longer able to re-establish themselves. The same immune-first logic extends to bacteria, fungal infections and other persistent challenges a horse's system would otherwise fight alone.
The company recommends a recovery regimen of two ounces twice daily for two weeks, stepped down to one ounce twice daily for a month, then one ounce daily as a maintenance dose. Gomer's notes that visible improvement typically appears within about thirty days, depending on the horse's starting condition and the severity of what it is facing.
A well-fed immune system pays dividends across the whole horse. Gomer's Inc. recommends Karbo Combo+ under normal, environmental, training and performance stress alike, because the same gut-centered support that resists disease also helps a horse hold condition through shipping, competition and seasonal change. The high levels of perna in the formula support joint comfort and healing, while the zinc and selenium content can help horses managing conditions tied to those minerals.
Feeding is straightforward and scales to body weight. For the first two weeks Gomer's recommends a morning and evening dose, then a single daily maintenance dose after that. A foal or a four hundred pound animal takes a half ounce per feeding, a six hundred pound horse three quarters of an ounce, an eight hundred pound horse one ounce, a thousand pound horse an ounce and a half, and a fifteen hundred pound horse two ounces. Karbo Combo+ is available in one, three, five and thirty pound sizes, and the pelleted form makes it easy to top-dress an existing ration.
Yes. Gomer's Inc. explains that twice-daily feeding is intended to keep the blood level consistent, but the full recommended daily amount fed once a day will have the same effect. The two-feeding schedule is most useful during the initial two-week loading period.
No. Karbo Combo+ is designed to complement Marquis during EPM treatment rather than interfere with it. Gomer's reports that keeping a horse on a maintenance dose afterward helps prevent the EPM protozoa from re-establishing in the animal.
Karbo Combo+ provides adequate vitamins for a maintenance level. Gomer's Inc. notes that performance horses or horses under heavy training stress will benefit from additional vitamins in their ration on top of the supplement.
Gomer's Inc. indicates that Karbo Combo+ typically shows decided improvement within about thirty days, with the exact timeline depending on the horse's general condition and how severe the issue being addressed is.
It can happen. When a horse with an unbalanced digestive flora first goes on Karbo Combo+, the rebalancing process may cause short-duration loose stools in many cases. This is a transient adjustment as the gut microbiome settles into a healthier balance.
Generally no. Karbo Combo+ already delivers a large number of probiotics in every gram, a minimum of 525 million CFU per ounce. Gomer's Inc. advises that adding a separate probiotic is unnecessary as long as the horse is kept on a maintenance dose.
No. The Karbo Combo+ formula contains no drugs, no antibiotics and no steroids. It is built from natural ingredients such as probiotics, saponins, oligosaccharides, antioxidants, glycoproteins, vitamins and minerals.
Karbo Combo+ is made by Gomer's Inc., a Wisconsin company whose Karbo and Epic II CL product lines grew out of more than fifty-five years of veterinary work by Dr. Russell C. Smith, DVM, and his wife Jeanette. The family business is carried on today by their son Peter Smith and his wife Lisa, continuing the same natural, immune-first philosophy.
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