Helping Horse Owners Make Informed Decisions
SilvaPlex® and Flexineb® by Wire 2 Wire Vet Products — Barrel Racing (SilvaPlex® and Flexineb® by Wire 2 Wire Vet Products offers real solutions to…)

SilvaPlex® and Flexineb® by Wire 2 Wire Vet Products

SilvaPlex® and Flexineb® by Wire 2 Wire Vet Products offers real solutions to horses suffering

Got a horse with breathing issues and want vet-developed nebulizer therapy plus silver?

Reviewed by Ann Pruitt, InfoHorse.com · Updated April 2026
SilvaPlex 100 PPM Chelated Silver natural immune support respiratory solution 16 oz bottle by Wire2Wire Vet Products
SilvaPlex 100 PPM Chelated Silver natural immune support respiratory solution 16 oz bottle by Wire2Wire Vet Products

SilvaPlex® and Flexineb® by Wire 2 Wire Vet Products offers real solutions to horses suffering with any form of breathing disabilities!

About Wire 2 Wire Vet Products- 2 Veterinarians Improving Horse Health!

Wire 2 Wire Vet Products, LLC was started in 2005 by Michael Cavey, DVM, and his wife Nancy Temple DVM married in 1994, dedicated horse owners and equestrians. Together they operate "Respite Farm, Inc", as a successful Thoroughbred breeding and racing operation breeding Eclipse Award winning Champions Uncle Mo and Champagne Room; they have been regular consignors to the major breeding sales in Kentucky.

Michael and Nancy’s goal to develop unique products to improve animal health care- especially within the equine world has become a reality, with their one-of-a-kind, flagship product “SilvaPlex®” and other related superior products.

Joining these amazing Husband/Wife Veterinarians is Richard Hoffberger, an avid horseman, and the owner of an influencial equine insurance agency. Together— this unique and extremely talented team have created a line of products second to none in the horse world… and, yes, these products help dogs, cats, goats and other farm animals also!

Introducing the One— the Only— SilvaPlex® !

Wire2Wire Vet Products, LLC is the exclusive distribution agent for SilvaPlex® products, manufactured in the USA… and it’s true— SilvaPlex® is ONE OF A Kind! The experience of our manufacturer in the areas of animal and personal care and environmental cleaning is both traditional and visionary. All Silvaplex products are manufactured from natural biodegradable raw materials that have been Ecocert-approved.

It’s the Patented next generation Chelated Silver and patented ComplexAg21™ that makes the difference in our Silvaplex® products. The Silvaplex® product Chief Chemist along with his collaborators, have been formulating personal care products and environmental cleaners since 1987. They also have great concern about Mother Earth and her importance in our life. Their experience and innovative ideas have been the key to our success.

SilvaPlex® is a safer, more effective product in a category that has remained stagnant for far too long. Animal and medical professionals prefer to use products that are naturally derived, non-toxic and child safe. SilvaPlex® is the one product containing all the ingredients to match these desired properties.

What Makes SilvaPlex® Products So Unique?

SilvaPlex® products are unlike anything else on the market thanks to their patented next-generation silver technology. Each formula is powered by:

  • Chelated Silver – Known for its antimicrobial, antifungal, and wound-healing properties
  • ComplexAg21™ – A patented silver-based compound with superior bioavailability
  • Natural Biodegradable Ingredients – Ecocert-approved and gentle on animals and the environment
  • Alcohol-Free, Non-Toxic Formulas – Safe for use around children, pets, and sensitive animals

You won’t find harsh chemicals or outdated ingredients in SilvaPlex®. This is truly the next generation of animal health care.

Is Your Performance Horse or Barrel Horse Suffering From Respiratory Problems?

Your horse is dependent on his or her lungs every moment of their life! From eating to sleeping to walking to performing, your horse’s lungs are vital to their ability to life and performance! Respiratory problems in horses are frequently the cause of poor sportive performances and can also impact the daily wellbeing of an animal. Historically there were several known types of respiratory disease in horses such as RAO (recurrent Airway Obstruction), Heaves, Copd and Inflammatory Airway Disease(IAD), which are now known under the umbrella term ‘Equine Asthma’ which is graded into three categories, Mild, Moderate & Severe.

It is up to horse owners to ensure that their horse gets everything possible to ensure the best possibility for full respiratory health.

Can SilvaPlex® Help?

Absolutely! SilvaPlex® is one of the most exciting breakthroughs in natural respiratory relief for horses. Their Silvaplex® Natural Immune Support and SilvaPlex® Homeopathic Throat Spray offer gentle, effective respiratory support that helps soothe your horse’s irritated airways, reduce mucus, and promote healthier breathing. Whether your horse suffers from dust, allergens, or diagnosed respiratory conditions like Heaves, RAO, IAD, or Equine Asthma, SilvaPlex® Throat Spray delivers a soothing solution you can trust.

Note: —This veterinarian-recommended formula is safe, non-toxic, and alcohol-free. And for deeper respiratory support, it can be used with our Flexineb® Nebulizer to deliver a fine mist of healing ingredients directly to the lungs.

What Other Conditions Can SilvaPlex Help My Horses or Dogs With?

Many veterinarians have found it to be helpful when dealing with situations like:

  • coughs
  • nasal discharges
  • allergies
  • infections
  • inflammation— and more!

How Often Should I Use it?

Silvaplex Immune Support or SilvaPlex® Homeopathic Throat Spray can be used daily for 5-7 days with follow-up once or twice weekly as needed or recommended by your veterinarian.

What If I Need A Nebulizer? and Why Is It So Effective?

A Nebulizer can carry our Silva Plex® directly into the lungs to fight infection! A Nebulizer is a “must have” for horses with respiratory ailments— especially performance horses! Wire2Wire Vet Products is a certified importer of the Flexineb® E3, an advanced equine nebulizer made in Ireland by Nortev. Unlike traditional systems with loud compressors and tangled tubing, Flexineb® is:

  • Cordless & Rechargeable
  • Silent in Operation
  • Flexible & Comfortable for your horse
  • Portable and Easy to Use anywhere on your property

Is It True That Our FLEXINEB Nebulizer is Quieter Than The Competition?

Yes and if you have a horse, like so many, that don’t appreciate loud sounds, our Nebulizer is for you! Our Flexineb® E3 system uses a vibrating membrane instead of a loud compressor to aerosolize medications or natural products like our SilvaPlex Immune Support and SilvaPlex® Homeopathic Throat Spray. This allows for targeted respiratory therapy and faster recovery with less stress on your horse.

It’s especially helpful for horses struggling with:

  • Chronic coughing
  • Nasal discharge
  • Dust or mold sensitivity
  • Seasonal respiratory issues
  • Performance loss due to airway inflammation

Note: Thousands of horses World-Wide have experienced relief and recovery with this revolutionary solution!

What Other Products Are in the SilvaPlex® Line?

In addition to the incredible Silvaplex® Immune Support and Throat Spray, Wire2Wire Vet Products offers a full line of SilvaPlex® products for equine skin, wounds, and hoof care.

In addition to the incredible Silvaplex® Immune Support and Throat Spray, Wire2Wire Vet Products offers a full line of SilvaPlex® products for equine skin, wounds, and hoof care.

Why Should I Choose SilvaPlex® Over Other Wound or Skin Care Products?

Most traditional wound care and respiratory products haven’t changed in decades. They may contain alcohol, iodine, or artificial dyes that irritate skin or tissue. Others may be poorly absorbed or simply don’t stay in place.

SilvaPlex® changes all of that by offering:

  • Modern, science-backed solutions
  • Natural, safe, biodegradable ingredients
  • Superior adherence and performance
  • No sting, no odor, no mess
  • Trusted by top veterinarians and serious horse owner

Give Your Horse the True Healing Power SilvaPlex® Offers!

Whether your horse is coughing from dust or has a more serious respiratory challenge, SilvaPlex® gives you a smarter, safer way to help them heal. The SilvaPlex line is trusted by veterinarians, groomers, and owners who can’t afford to get it wrong, but need a trusted source for real results! Safe, Effected, Backed by Science and made with a sincere Love for the animals YOU love. Visit www.w2wvp.com Today- and discover the SilvaPlex® difference!



SilvaPlex 100 PPM Chelated Silver natural immune support respiratory solution 16 oz bottle by Wire2Wire Vet Products
SilvaPlex 100 PPM Chelated Silver natural immune support respiratory solution 16 oz bottle by Wire2Wire Vet Products

What is SilvaPlex® and how does it help a hard-running barrel horse breathe?

SilvaPlex® is a naturally derived, non-toxic respiratory and immune solution built on patented Ag21™ Chelated Silver, delivered at a concentration of 100 PPM (parts per million). Where a barrel horse is asked to fire through dusty arena footing, long trailer hauls, and back-to-back show weekends, SilvaPlex is engineered to support overall wellness during show season, post-trailer travel, or working in dusty environments. One owner reported her mare with a three-year asthma history "finally didn't cough when I exercised her" after the first week and went on to run barrels without coughing.

SilvaPlex chelated silver supporting clearer horse breathing and equine respiratory health
SilvaPlex chelated silver supporting clearer horse breathing and equine respiratory health

Why chelated silver instead of the colloidal or ionic silvers you see everywhere?

Most silver products use unstable "colloidal" or "ionic" suspensions; SilvaPlex® is powered by the patented Complex Ag21™, an advanced chelated silver bonded to citric acid for a stable, evenly distributed solution that stays active where other silvers fail. That molecular stability is the whole point: the silver remains active in the bottle and in the airway. SilvaPlex is also pH-balanced, alcohol- and Triclosan-free, FDA-registered, and made per FDA GMP (Good Manufacturing Practice) guidelines.

Performance horse at work supported by SilvaPlex respiratory and immune solution from Wire2Wire Vet Products
Performance horse at work supported by SilvaPlex respiratory and immune solution from Wire2Wire Vet Products

Who makes it, and why should a barrel racer trust two veterinarians?

Wire2Wire Vet Products, LLC was founded in 2005 by Michael Cavey, DVM (College of William and Mary; University of Georgia College of Veterinary Medicine) and equine surgeon Nancy Temple, DVM (University of Illinois, with a residency at the Marion duPont Equine Hospital). The company runs on a single principle — they only sell products they use on their own animals. The Caveys' Respite Farm in Kentucky bred Eclipse Award champions including Uncle Mo and Champagne Room, so this is performance-horse medicine, not marketing.

SilvaPlex Natural Immune Support chelated silver solution detail by Wire2Wire Vet Products
SilvaPlex Natural Immune Support chelated silver solution detail by Wire2Wire Vet Products

How do you dose SilvaPlex® for the airway?

SilvaPlex® is sold as a concentrate that can be used at three strengths by dilution: 100 PPM undiluted for intensive support as directed by veterinary professionals, 50 PPM (1:1) as standard maintenance for large animals, and 25 PPM (1:3) for daily wellness in smaller animals and pets. The owner of the asthmatic barrel mare used 20cc twice daily for a week, then once daily the second week, then every other day. SilvaPlex pairs naturally with a nebulizer for airway delivery.

What is Flexineb® and how does it get the therapy into the lungs?

Flexineb® E3 is a portable, re-usable, silent equine nebuliser that produces an ultra-fine mist of aerosolized drug or natural therapy solution — no noisy compressor, hoses, or wires. It runs from a rechargeable battery-powered controller behind a flexible mask with a clear aerosol chamber and medication cup, so the horse can be treated quietly in the stall or at the trailer. Wire2Wire is a certified importer of the Flexineb® E3, manufactured in Ireland by Nortev, and it is used worldwide to manage Equine Asthma (Mild, Moderate & Severe), formerly known as RAO/Heaves, Copd, and Inflammatory Airway Disease (IAD).

What does it cost and how do you order?

SilvaPlex® 100 PPM Chelated Silver respiratory solution is $31.95 in 8 oz. and 16 oz. bottles, with 12-bottle case pricing available. The Flexineb® E3 Equine Nebulizer is $1,175.00; the Flexineb® E3 Controller Kit is $285.00; and the Mask Assembly with Aerosol Holding Chamber Kit is $465.00. Order directly from wire2wirevetproducts.com or reach the team at (859) 953-1574 or, 1040 Hume-Bedford Road, Paris, Kentucky 40361.

Share This Solution
The Solution Section (FAQ)
Is Your Performance Horse or Barrel Horse Suffering From Respiratory Problems?
Your horse is dependent on his or her lungs every moment of their life! F rom eating to sleeping to walking to performing, your horse s lungs are vital to their ability to life and performance! Respiratory problems in horses are frequently the cause of poor sportive performances and can also impact the daily wellbeing of an animal. Historically there were several known types of respiratory disease in horses such as RAO (recurrent Airway Obstruction), Heaves, COPD and Inflammatory Airway Disease(IAD), which are now known under the umbrella term Equine Asthma which is graded into three categories, Mild, Moderate & Severe. It is up to horse owners to ensure that their horse gets everything possible to ensure the best possibility for full respiratory health.
Why Should I Choose SilvaPlex Over Other Wound or Skin Care Products?
Most traditional wound care and respiratory products haven t changed in decades. They may contain alcohol, iodine, or artificial dyes that irritate skin or tissue. Others may be poorly absorbed or simply don t stay in place.
What Other Products Are in the SilvaPlex Line?
In addition to the incredible Silvaplex Immune Support and Throat Spray, Wire2Wire Vet Products offers a full line of SilvaPlex products for equine skin, wounds, and hoof care.
What Makes SilvaPlex Products So Unique?
SilvaPlex products are unlike anything else on the market thanks to their patented next-generation silver technology. Each formula is powered by:
What is SilvaPlex used for in horses?
SilvaPlex is a naturally derived, non-toxic 100 PPM chelated silver solution that supports immune response, clearer breathing, wound care, and skin health in horses. For respiratory use it is intended to support overall wellness during show season, post-trailer travel, or work in dusty environments. It can be given orally diluted or, very commonly, nebulized so the fine mist reaches the airways directly.
What makes SilvaPlex different from colloidal or ionic silver?
Most silver products on the market are unstable colloidal or ionic suspensions that can lose potency. SilvaPlex is powered by the patented Complex Ag21 chelated silver, which is bonded to citric acid for a stable, evenly distributed solution. That chelation keeps the silver active and effective where other silvers fail.
What is Ag21 chelated silver?
Ag21 is Wire2Wire's patented chelated silver technology. The silver is chemically bonded (chelated) to citric acid so it stays evenly distributed and molecularly stable in solution, rather than clumping or settling like colloidal silver. The result is a 100 PPM silver concentration that remains active in the bottle and in use.
How do I dose SilvaPlex for my horse's breathing?
SilvaPlex is a concentrate that can be used at three strengths by dilution: 100 PPM undiluted for intensive support as directed by veterinary professionals, 50 PPM (1:1) for standard large-animal maintenance, and 25 PPM (1:3) for daily wellness. One barrel-racing owner used 20cc twice daily for a week, then once daily the second week, then every other day. Always follow your veterinarian's guidance for respiratory protocols.
Can SilvaPlex help a barrel horse that coughs when exercised?
That is exactly the scenario one customer described. Her mare had a three-year asthma history, and after the first week on SilvaPlex she reported the mare 'finally didn't cough when I exercised her' and went on to run barrels without coughing. Results vary by horse, and any chronic respiratory issue should be evaluated by your veterinarian.
What is Flexineb and how does it work?
Flexineb E3 is a portable, re-usable, silent equine nebuliser that turns a drug or natural therapy solution into an ultra-fine mist the horse inhales. It runs on a rechargeable battery-powered controller and uses a flexible mask with a clear aerosol chamber and medication cup, eliminating the noisy compressor, hoses, and wires of older nebulizers. This lets you treat a horse quietly in the stall or at the trailer.
Who makes Flexineb and is Wire2Wire an authorized seller?
Flexineb E3 is manufactured in Ireland by Nortev. Wire2Wire Vet Products is a certified importer and authorized reseller of the Flexineb E3 in the United States, so you are buying the genuine device with proper support.
What does Flexineb treat?
Flexineb is used to manage equine respiratory conditions now classified as Equine Asthma in Mild, Moderate, and Severe grades. This includes conditions historically called RAO (Recurrent Airway Obstruction), Heaves, COPD, and Inflammatory Airway Disease (IAD). Thousands of horses worldwide use it to keep working, rehabilitate from acute illness, and manage chronic airway disease.
How much does SilvaPlex cost?
The SilvaPlex 100 PPM Chelated Silver respiratory and immune solution is $31.95. It is available in 8 oz. and 16 oz. bottles, with 12-bottle case pricing also offered for both sizes.
How much does the Flexineb system cost?
The Flexineb E3 Equine Nebulizer is $1,175.00. Individual components are also available: the Flexineb E3 Controller Kit is $285.00, the Mask Assembly with Aerosol Holding Chamber Kit is $465.00, and a Soft Shell Mask with Exit Valve and Straps is $395.00 (marked down from $435.00).
Who founded Wire2Wire Vet Products?
Wire2Wire Vet Products, LLC was founded in 2005 by Michael Cavey, DVM, his wife and equine surgeon Nancy Temple, DVM, and equine-industry executive Richard Hoffberger. Dr. Cavey is a graduate of the College of William and Mary and the University of Georgia College of Veterinary Medicine; Dr. Temple trained at the University of Illinois with a residency at the Marion duPont Equine Hospital.
What is Respite Farm's connection to the company?
Respite Farm is the Caveys' Thoroughbred breeding and racing operation in Kentucky, managed by Dr. Nancy Temple. The farm bred Eclipse Award-winning champions including Uncle Mo and Champagne Room. The same standards used on those elite racehorses inform the products Wire2Wire develops and sells.
Is SilvaPlex safe to use?
SilvaPlex is described as naturally derived and non-toxic, pH-balanced, and free of alcohol and Triclosan. The Material Safety Data Sheet states that when used as directed it is safe and effective with no personal precautions other than avoiding contact with the eyes. It is an FDA-registered homeopathic product made under FDA GMP (Good Manufacturing Practice) guidelines.
Is SilvaPlex only for horses?
No. Wire2Wire began with elite equine performance and has grown into a multi-species operation providing veterinarian-formulated care for horses, cattle, dogs, and cats. One customer used SilvaPlex in a nebulizer to help lessen congestion in a teacup Yorkie, and the chelated silver line is used for immune, wound, and skin care across species.
Besides the respiratory solution, what other SilvaPlex products are available?
The SilvaPlex line includes a Throat Spray for breathing comfort, Woundcare in gel or spray form for cuts, abrasions, lacerations, and minor burns, and a Shampoo for coat and skin health. All are built on the same Ag21 chelated silver and an advanced chitosan compound that supports the skin barrier against environmental stressors.
Can SilvaPlex and Flexineb be used together?
Yes, and that pairing is a core reason both products live under one brand. SilvaPlex provides a stable chelated silver solution, and the Flexineb E3 nebulizer aerosolizes solutions into an ultra-fine mist the horse inhales, delivering airway support directly to the lungs. This combination lets owners run a quiet, drug-free or veterinarian-directed respiratory protocol at home or at shows.
How do I order or contact Wire2Wire Vet Products?
You can order the full SilvaPlex and Flexineb lines directly at wire2wirevetproducts.com. The company is located at 1040 Hume-Bedford Road, Paris, Kentucky 40361, and can be reached by phone at (859) 953-1574 or by email at [email protected].

Contact SilvaPlex® and Flexineb® by Wire 2 Wire Vet Products

Call Email
Ann Pruitt
Contact Ann Pruitt
InfoHorse.com