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Anhidrosis Prevention By ONE AC — Health (The feed supplement that helps non-sweating horses sweat again)

Anhidrosis Prevention By ONE AC

The feed supplement that helps non-sweating horses sweat again.

Got a horse that can't sweat properly in the heat and needs anhidrosis support?

Reviewed by Ann Pruitt, InfoHorse.com · Updated May 2026
Barrel racer galloping her chestnut horse around a sunlit arena during summer competition
Barrel racer galloping her chestnut horse around a sunlit arena during summer competition

ONE AC

is a nutritional feed supplement made by Mpco for horses with anhidrosis — the partial or total inability to sweat, sometimes called “dry coat.” When a horse can no longer cool itself properly in heat and humidity, even light work becomes risky. ONE AC is formulated to give the horse the raw materials it needs to return to normal sweating, and according to the company many anhidrotic horses begin sweating again within 10 to 14 days. It is an everyday powder you stir into feed, and the company states it carries no banned substances, so it can be used on horses in competition. You can order ONE AC around the clock through the secure shopping cart at nonsweater.com or by phone, and a distributor list is published on the site for buyers who prefer to shop locally. As with any supplement, the makers advise you to consult your veterinarian before starting your horse on ONE AC.

ONE AC equine feed supplement jar from MPCO with green label for non-sweating horses
ONE AC equine feed supplement jar from Mpco with green label for non-sweating horses

What Is ONE AC?

ONE AC is an equine feed supplement built around three working ingredients — L-tyrosine, niacin and vitamin C (ascorbic acid) — alongside supporting B-vitamins. Rather than masking the symptoms of a non-sweating horse, it is designed to supply the nutrients the body draws on when it produces sweat. The product was field-tested at the University of Florida, and Mpco reports that ONE AC has proven helpful for the large majority of the anhidrotic horses studied. It is sold as a fine powder measured by the teaspoon, is safe to feed to performance horses, and the company notes it can be used in pregnant and lactating mares. The jar carries a clean, no-nonsense green-and-white label so it is easy to recognize on the feed-room shelf.

Close portrait of a flaxen-maned chestnut horse standing in golden autumn light
Close portrait of a flaxen-maned chestnut horse standing in golden autumn light

What Is Anhidrosis and How Does ONE AC Help?

Anhidrosis is the partial or total loss of the ability to sweat, and it is most common in hot, humid climates such as Florida and Louisiana. A horse that cannot sweat loses its primary cooling system; according to Mpco, even at rest a non-sweater’s body temperature may climb to between 102 and 103 degrees, and the danger rises sharply with work. ONE AC’s developer attributes the condition to a shortage of dopamine, theorizing that the body spends available dopamine first on the brain, then the cardiovascular system, and last on sweating — so when supply runs short, sweating is the function that fails. The L-tyrosine in ONE AC acts as a building block for dopamine and related catecholamines, while the niacin and vitamin C support the process. The company says horses generally start sweating again within ten to fourteen days, and recommends easing the horse out of hard training for the first few weeks while the system recovers. These are the advertiser’s claims; always consult your veterinarian before treating a non-sweating horse.

"My non-sweater is sweating after about 10 days on One AC." JBEquestrian

How Do I Feed It and Where Do I Buy?

Feeding ONE A C is simple. For an average horse of roughly 950 to 1,100 pounds, the label directs one teaspoon twice daily, morning and evening, mixed into the regular ration. Owners often report seeing renewed sweating within the first couple of weeks, and the company suggests giving the supplement time and a lighter workload early on so the horse’s system can respond. ONE AC is available to order any time of day through the secure online shopping cart at nonsweater.com, and the company maintains a published distributor list for those who would rather buy from a local tack or feed store. Because it contains no banned ingredients, ONE AC is suited to horses that are actively showing and competing. Before starting any new supplement, the makers recommend a conversation with your own veterinarian about your horse’s specific situation.

Owner gently grooming the neck of a calm dappled gray horse beside a wooden barn
Owner gently grooming the neck of a calm dappled gray horse beside a wooden barn
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The Solution Section (FAQ)
How long before my horse starts sweating again on ONE AC?

MPCO reports that horses generally start sweating again within ten to fourteen days of starting on ONE AC. The company recommends easing the horse out of hard training for roughly the first three weeks so its system has time to respond. Individual results vary, so monitor your horse and consult your veterinarian.

What is in ONE AC?

ONE AC is built around three working ingredients — L-tyrosine, niacin and vitamin C (ascorbic acid) — supported by additional B-vitamins. The L-tyrosine acts as a precursor for dopamine production, which the developer links to a horse’s ability to sweat normally.

How much ONE AC do I feed?

For an average horse weighing roughly 950 to 1,100 pounds, the label directs one teaspoon twice daily — morning and evening — mixed into the normal feed ration.

Is ONE AC safe for horses in competition?

According to MPCO, ONE AC contains no banned ingredients, making it suitable for horses that are actively showing and competing. The company also states it can be used in pregnant and lactating mares. Always confirm with your veterinarian and your competition body’s rules.

What is anhidrosis in horses?

Anhidrosis is the partial or total inability to sweat, sometimes called “dry coat.” It is most common in hot, humid climates and removes a horse’s main way of cooling itself. MPCO notes that even at rest a non-sweater’s body temperature may rise to between 102 and 103 degrees.

Has ONE AC been tested?

Yes. ONE AC was field-tested at the University of Florida, and MPCO reports it proved helpful for the large majority of the anhidrotic horses in those tests. As with any supplement, the company advises consulting your veterinarian before use.

Where can I buy ONE AC?

ONE AC can be ordered any time through the secure online shopping cart at nonsweater.com. The company also publishes a distributor list on its website for buyers who prefer to purchase from a local tack or feed store.

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Ann Pruitt
Contact Ann Pruitt
InfoHorse.com