Michelle Wagner

NitrOxidePLUS, offered by Wag-N-Will Farm, is the best choice for long term Nutritional Support

Got a stressed performance horse and want long-term natural nutritional support?

Reviewed by Ann Pruitt, InfoHorse.com · Updated May 2026

NitrOxide equine blood-flow and laminitis nutritional support supplement tub by Total Health Enhancement

Michelle Wagner

Nutritional Support With NitrOxidePLUS offered by Wag-N-Will Farm
NitrOxidePLUS, offered by Wag-N-Will Farm, is the best choice for long term Nutritional Support for the relief of stress and overall Equine Fitness.

About Michelle Wagner And Total Health Enhancement Inc.
Total Health Enhancement, Inc. provides revolutionary solutions to various forms of pain, ailment and increased performance through all-natural products designed to increase the flow of nitric oxide throughout the body. Studies have shown that nitric oxide is key to the body's overall health and performance. Years of positive testing and research allow us to offer our products designed to increase the body's natural healing process and performance, with all-natural ingredients. Our products will improve your personal health issues and our equine products will provide all natural options for equine health.

Michelle first started using the T.H.E products after she won the Wpra Total Health Enhancement Division Tour and received free samples. She used the product for a year and was so impressed with the results she was having on her Mare she decided to become a Dealer for the company. She has been very impressed with the range of products that Total Health has and the many people that come up to her and tell her their wonderful stories and how the product has help them and their equine animals

NitrOxidePLUS™
Product for long term Nutritional Support for the relief of stress and overall Equine Fitness. NitrOxide™ is non-specific in its formulation and will support nitric oxide for a range of conditions. It has been designed for the long term maintenance of health. Each 2 lb. Jar of powder contains 32 servings for a 1000 lb. horse (1 ounce = 1 serving for a 1000 lb. horse) NitrOxidePLUS™ provides the nutrients a horse's body needs to form neurotransmitters that promote blood flow. NitrOxide™ combines selected neurotransmitter-precursors with all-natural ingredients that support neurotransmitter synthesis.

What Is The Proper Dosing For NitrOxidePLUS™?
It really depends on the case of the horse; each bottle has 32 servings for 1000-pound horse. Please email Michelle when your order to advise her of your horses weight and condition so she can give you proper dosing instructions.

Why Is Nitric Oxide So Important For My Horse?

Nitric oxide is a chemical produced in the body that keeps blood vessels dilated, increasing blood flow. Nitric oxide also has a wide variety of other effects, including killing bacteria and viruses and promoting the bodies own healing of wounds and ulcers.

Stress, aging, injuries, intense exercise, and fighting disease-causing organisms can all deplete the body of nitric oxide. A human or animal that has insufficient levels of nitric oxide will be unable to perform to the best of its abilities. Depletion of nitric oxide may be involved in a variety of health problems including laminitis (founder) in horses, gastric ulcers and infertility. Just as a chain breaks at its weakest link, insufficient production of nitric oxide can affect the performance of all humans and animals and surface in different ailments.

Order NitrOxidePLUS™ Today!
Email Michelle Wagner directly at her website so you can get a discount when your order! Help your horse heal naturally with NitrOxidePLUS™, which is unique because it is not a drug and works with your horses system to heal naturally and efficiently.

What exactly is NitrOxide and what does it target?

NitrOxide is a daily nutritional support powder from Total Health Enhancement Corp, marketed under the T.H.E. Equine Edge line, formulated to promote the long-term health of a horse's blood-flow system. The company positions it specifically as nutritional support for acute or chronic laminitis, anhydrosis (the inability to sweat), and general circulation issues. Rather than masking symptoms, the blend is built to increase nutrient delivery throughout the body's systems using natural herbs, amino acids, and vitamins. It ships as a feed top-dress in five sizes ranging from 30 to 400 servings.

NitrOxide back label showing active ingredient list and feeding directions for horses

Who formulates the supplement behind this listing?

Total Health Enhancement Corp was founded in 1996 by Bob Fogli, who pairs a lifelong passion for horses with a degree in Nutritional Science earned through a naturopathic university. Fogli serves as CEO and is the formulator of every product in the T.H.E. Equine Edge catalog, which spans equine and canine nutrition. The company operates out of 36 Greco Lane, Warwick, RI 02886, and reaches customers nationwide at (888) 422-8398 and. Office hours run 7:00am - 3:30pm EST.

T.H.E. Super Daily complete equine daily supplement with Nitric Oxide delivery system

What goes into the NitrOxide blend?

NitrOxide is a proprietary blend whose active ingredients include L-Arginine Base, Choline Bitartrate, Vitamin E, Vitamin C (Ascorbic Acid), Turmeric Organic, Horse Chestnut, N-Acetyl-L-Cysteine, L-Glutamic Acid, L-Histidine HCL, and Citrus Bioflavonoid. The amino-acid and vitamin foundation continues with Vitamin B3 (Niacinamide), Vitamin B5 (Calcium D-Pantothenate), Vitamin B6 (Pyridoxine HCL), L-Glutamine, Vitamin B1 (Thiamine HCL), L-Citrulline DL-Malate, Echinacea Purpurea, and Vitamin B12 (Methylcobalamin). Minerals and finishing nutrients include Manganese Gluconate, Iron, Himalayan Salt, Zinc Gluconate Dihydrate, Folic Acid, and Biotin. T.H.E. Equine Edge states it uses natural and organic vitamins, herbs, amino acids, and minerals with no fillers, preservatives, or added sugars.

T.H.E. Super Daily back label with proprietary blend ingredients for horses

How does the Nitric Oxide approach work?

The formula is built around a Nitric Oxide delivery system, anchored by the amino acids L-Arginine and L-Citrulline, intended to support healthy blood flow so nutrients reach the tissues that need them. Through that improved circulation, the company connects the technology to hooves, digestion, joints, muscle strength, bone density, and immune function. For a 1,000-lb horse the recommended protocol is two level scoops daily for the first five days, then one level scoop daily thereafter as a feed top-dress. Because the ingredients are natural, the company notes physical attributes such as color may vary from lot to lot.

Is NitrOxide right for your horse and your discipline?

The line is designed to be safe for Insulin Resistant (IR) horses, making it a consideration for metabolic and laminitic cases where sugar load is a concern. For competition barns, Total Health Enhancement labels products as "CS Compliant" (always show safe) or "CS Available" (can be made USEF/FEI compliant by removing certain ingredients), so riders in regulated disciplines can request a competition-legal version. The company also offers custom formulas to address difficult, recurring cases; owners can send a horse's CBC and Chemistry Panel with a brief history to for a tailored blend.

How do you buy it and what is the guarantee?

NitrOxide starts at $141.00, with serving counts of 30, 80, 160, 240, and 400 available directly from totalhealthenhance.com. Orders ship from the Warwick, RI facility via UPS and Usps, and the company backs purchases with a 100% Satisfaction Guarantee allowing returns, refunds, or exchanges within 45 days. Questions on dosing, custom blends, or show compliance can go to (888) 422-8398 or.

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The Solution Section (FAQ)

What is NitrOxidePLUS™ and what does it support?

NitrOxidePLUS™, offered by Wag-N-Will Farm, is a product for long-term nutritional support for the relief of stress and overall equine fitness. It provides the nutrients a horse's body needs to form neurotransmitters that promote blood flow, combining selected neurotransmitter-precursors with all-natural ingredients that support neurotransmitter synthesis.

Why is nitric oxide so important for my horse?

Nitric oxide is a chemical produced in the body that keeps blood vessels dilated, increasing blood flow, and it also helps kill bacteria and viruses and promotes the body's own healing of wounds and ulcers. Stress, aging, injuries, intense exercise, and fighting disease-causing organisms can all deplete the body of nitric oxide, and depletion may be involved in problems including laminitis (founder), gastric ulcers and infertility.

How many servings are in a jar of NitrOxidePLUS™?

Each 2 lb. jar of powder contains 32 servings for a 1000 lb. horse, where 1 ounce equals 1 serving for a 1000 lb. horse.

How do I get the proper dosing for my horse?

Proper dosing really depends on the individual horse. The company recommends you email Michelle when you order to advise her of your horse's weight and condition so she can give you proper dosing instructions.

Is NitrOxidePLUS™ a drug?

No — NitrOxidePLUS™ is not a drug. It is unique in that it works with your horse's system to help it heal naturally and efficiently, supporting the body's own production of nitric oxide rather than acting as a medication.

What is NitrOxide used for in horses?

NitrOxide is a daily nutritional support powder formulated to promote the long-term health of a horse's blood-flow system. Total Health Enhancement markets it specifically for acute or chronic laminitis, anhydrosis (the inability to sweat properly), and general circulation issues. It works by helping increase nutrient delivery throughout the body's systems.

Who makes NitrOxide and the T.H.E. Equine Edge line?

It is made by Total Health Enhancement Corp, founded in 1996 by Bob Fogli, who holds a degree in Nutritional Science from a naturopathic university. Fogli is the CEO and the formulator of every T.H.E. Equine Edge product. The company is based at 36 Greco Lane, Warwick, RI 02886.

What are the active ingredients in NitrOxide?

NitrOxide is a proprietary blend whose actives include L-Arginine Base, Choline Bitartrate, Vitamin E, Vitamin C, Turmeric Organic, Horse Chestnut, N-Acetyl-L-Cysteine, L-Glutamic Acid, L-Histidine HCL, and Citrus Bioflavonoid. It also contains B-vitamins (B1, B3, B5, B6, B12), L-Glutamine, L-Citrulline DL-Malate, Echinacea Purpurea, Manganese Gluconate, Iron, Himalayan Salt, Zinc Gluconate Dihydrate, Folic Acid, and Biotin.

How is NitrOxide dosed for a typical horse?

For a 1,000-lb horse the recommended protocol is two level scoops daily for the first five days, then one level scoop daily thereafter. It is fed as a top-dress over the horse's normal feed. Owners with picky eaters can start with a small amount mixed into mash or treats and build up to the full serving.

How much does NitrOxide cost?

NitrOxide starts at $141.00 on totalhealthenhance.com. It is sold in five serving sizes: 30, 80, 160, 240, and 400 servings, so the larger counts spread the cost over a longer feeding period. Buying directly from the manufacturer ensures you receive the current formulation.

Is NitrOxide safe for insulin-resistant (IR) horses?

Yes. Total Health Enhancement states that its formulas are safe for Insulin Resistant horses, and it does not use fillers, preservatives, or added sugars. This makes the line a consideration for metabolic and laminitic horses where controlling sugar intake matters. As always, owners managing a diagnosed condition should coordinate with their veterinarian.

Is the supplement legal for USEF or FEI competition?

Total Health Enhancement labels products as either "CS Compliant" (always show safe) or "CS Available" (can be made compliant on request). For USEF/FEI-regulated disciplines, certain ingredients are removed to produce a competition-legal version. Riders in regulated competition should request the compliant version before ordering.

How does the Nitric Oxide delivery system work?

The formula is anchored by amino acids such as L-Arginine and L-Citrulline that are associated with nitric oxide production, which the company connects to healthy blood flow. By supporting circulation, the system is intended to help carry nutrients to the tissues that need them. The company links this approach to hooves, digestion, joints, muscle strength, bone density, and immune function.

Can NitrOxide help a horse with anhydrosis (non-sweater)?

Total Health Enhancement lists anhydrosis as one of the conditions NitrOxide provides nutritional support for, alongside laminitis and blood-flow issues. The blend's circulation-focused amino acids and B-vitamins are aimed at supporting the body systems involved. Results vary by horse, and chronic non-sweaters should remain under veterinary care, especially in hot climates.

What other products does T.H.E. Equine Edge offer?

Beyond NitrOxide, the equine catalog includes T.H.E. Super Daily (a complete daily supplement with 50+ actives), Performance, T.H.E. Muscle Mass, Electrolyte PLUS, natural Vitamin E, Hive/Allergy, Gray-White Maintenance, Hair & Coat, Calming/Focus Cookies, and Red Blood Cell support. The company also makes a full canine line covering joints, heart, immune, digestive, and calming needs.

Does Total Health Enhancement use fillers or added sugar?

No. The company states it uses natural and organic vitamins, herbs, amino acids, and minerals with no fillers, preservatives, or added sugars. This clean-label approach is part of why the line is positioned as safe for insulin-resistant horses. Because the ingredients are natural, physical attributes can differ slightly from lot to lot.

Are custom formulas available for difficult cases?

Yes. Total Health Enhancement offers custom formulas designed to help solve difficult, recurring cases. To request one, owners send their horse's CBC and Chemistry Panel along with a brief history to [email protected]. The company's formulator then builds a blend tailored to that individual animal.

How long until I see results from NitrOxide?

The company does not publish a fixed timeline, and response times vary with the individual horse and the condition being supported. Because it is a nutritional support product rather than a medication, many owners feed it consistently over weeks while monitoring their horse. For specific expectations, the company invites questions at (888) 422-8398 or [email protected].

Can I give NitrOxide alongside prescribed medications?

The company advises separating supplements and any prescribed drugs by at least 3 to 4 hours apart. This timing guidance applies generally across their product line. Owners whose horses are on veterinary medications should confirm the plan with their veterinarian before adding any supplement.

How do I contact Total Health Enhancement and what are their hours?

You can reach Total Health Enhancement Corp toll-free at (888) 422-8398 or by email at [email protected]. Office hours are 7:00am - 3:30pm EST. The mailing address is 36 Greco Lane, Warwick, RI 02886.

How does NitrOxide ship, and is there a guarantee?

Orders ship from the Warwick, RI facility via UPS and USPS. Total Health Enhancement backs purchases with a 100% Satisfaction Guarantee, offering returns, refunds, or exchanges within 45 days of purchase. This lets owners try the product with confidence.

What is Wag-N-Will Farm's connection to NitrOxide?

Wag-N-Will Farm, associated with Michelle Wagner, is featured on InfoHorse offering NitrOxidePLUS for long-term nutritional support, stress relief, and overall equine fitness. The underlying product is NitrOxide from Total Health Enhancement Corp, the formulator and manufacturer. For product specifications, pricing, and ordering, the manufacturer's site at totalhealthenhance.com is the primary source.