to help heal and prevent gastric ulcers

GastroPLUS™ is a nutritional supplement designed to minimize the potential for, and effects

Got a horse battling ulcers and want a supplement to restore proper stomach blood flow?

Reviewed by Ann Pruitt, InfoHorse.com · Updated June 2026

GastroPLUS equine gastric ulcer supplement container with measuring scoop from T.H.E. Equine Edge

to help heal and prevent gastric ulcers

GastroPLUS™ offered by Wag-N-Will Farm
GastroPLUS™ is a nutritional supplement designed to minimize the potential for, and effects of, ulcers by promoting production of neurotransmitters needed for proper blood flow to the stomach.

About Michelle Wagner And Total Health Enhancement Inc.
Total Health Enhancement, Inc. provides revolutionary solutions to various forms of pain, ailment and increased performance through all-natural products designed to increase the flow of nitric oxide throughout the body. Studies have shown that nitric oxide is key to the body's overall health and performance. Years of positive testing and research allow us to offer our products designed to increase the body's natural healing process and performance, with all-natural ingredients. Our products will improve your personal health issues and our equine products will provide all natural options for equine health.

Michelle first started using the T.H.E products after she won the Wpra Total Health Enhancement Division Tour and received free samples. She used the product for a year and was so impressed with the results she was having on her Mare she decided to become a Dealer for the company. She has been very impressed with the range of products that Total Health has and the many people that come up to her and tell her their wonderful stories and how the product has help them and their equine animals.

GastroPLUS™
Gastric ulcers occur in the majority of horses and cause significant damage before any symptoms can be noticed. Studies indicate that 90% of all adult horses and 50% of foals under the age of 6 months that have been scoped have shown to have gastric ulcers. Both stress and intense exercise deplete neurotransmitters crucial for the adequate blood flow to the stomach. This decreased blood flow reduces the production of mucus necessary to protect the stomach lining from stomach acid. The result is ulceration of the stomach lining. GastroPLUS™ supplies the necessary precursors for the production of the necessary neurotransmitters for increasing blood flow. Each 2 lb. Jar of powder contains 32 servings for a 1000 lb. horse (1 ounce = 1 serving for a 1000 lb. horse)

GastroPLUS™ is a nutritional supplement that is designed to help heal and prevent gastric ulcers in horses by supporting production of nitric oxide.

Why Is Nitric Oxide So Important For My Horse?

Nitric oxide is a chemical produced in the body that keeps blood vessels dilated, increasing blood flow. Nitric oxide also has a wide variety of other effects, including killing bacteria and viruses and promoting the bodies own healing of wounds and ulcers.

Stress, aging, injuries, intense exercise, and fighting disease-causing organisms can all deplete the body of nitric oxide. A human or animal that has insufficient levels of nitric oxide will be unable to perform to the best of its abilities. Depletion of nitric oxide may be involved in a variety of health problems including laminitis (founder) in horses, gastric ulcers and infertility. Just as a chain breaks at its weakest link, insufficient production of nitric oxide can affect the performance of all humans and animals and surface in different ailments.

What Is The Proper Dosing For GastroPLUS™?
In order to get the most out of your nitric oxide delivering products from Total Health Enhancement, please use the following recommendations:

These products are amino acid compounds; they go after proteins, so as empty a stomach as possible is very important. Feed in the stomach upsets the synergy of the ingredients, rendering it weak. With no food in the stomach, there will be an insulin reaction in the small intestine, delivering the full dosage of the active ingredients immediately into the bloodstream. Allowing the horse even small treats or to nibble on the ground is only wasting the product.

Note: Please emailMichellewhen your order to advise her of your horses weight and condition so she can give you proper dosing instructions.

Order GastroPLUS™ Today!
Email Michelle Wagner directly at her website so you can get a discount when you order GastroPLUS™ Today!

What is GastroPLUS® and how does it differ from acid blockers?

GastroPLUS® is an all-natural nutritional supplement from T.H.E. Equine Edge formulated to aid in the healing and prevention of equine gastric ulcers. Rather than suppressing stomach acid the way many ulcer products do, GastroPLUS® supports the horse's own ability to produce more protective mucus in the stomach lining, helping the horse control and contain gastric acid naturally. The company notes that acid-suppressing products can cause a rebound effect: when a horse comes off them, the body overcompensates and produces too much acid, turning ulcer management into a vicious cycle. GastroPLUS® is designed to break that cycle by working with the horse's physiology instead of against it.

GastroPLUS back label showing proprietary amino acid vitamin and mineral ingredient blend

What is inside the proprietary blend?

GastroPLUS® is a proprietary blend of amino acids, proteins, vitamins, and minerals curated for lasting gut health. The label lists L-Arginine, L-Glutamine, L-Glutamic Acid, L-Alanine, Beta-Alanine, L-Tyrosine, L-Histidine, N-Acetyl-L-Cysteine, Papaya, Aloe, Turmeric, Bromelain, Fenugreek Seed, Choline Bitartrate, Vitamin C, Vitamin E, the B-vitamins (Thiamine, Riboflavin, Pyridoxine, Niacinamide, Pantothenic Acid, Biotin, Folic Acid, Methylcobalamin), plus Zinc Gluconate, Manganese Gluconate, Iron, Selenium, and Himalayan Salt. T.H.E. Equine Edge states it uses natural and organic vitamins, herbs, amino acids, and minerals with no fillers, preservatives, or added sugars.

GastroPLUS equine ulcer supplement product feature image from Total Health Enhancement

Who makes GastroPLUS® and what is the science behind it?

GastroPLUS® is produced by Total Health Enhancement Corp under its T.H.E. Equine Edge brand, a company with over 20 years of equine formulation experience. Its formulas draw on Nobel Prize-winning science about Nitric Oxide (the Nitric Oxide Pathway), which increases blood flow to damaged tissue and to tissues under high demand or stress. Since 2010 the company has concentrated on thoroughbred and quarter horse racing as well as dressage, hunter/jumper, barrel racing, team roping, polo, reining, and pleasure riding. The company can also build custom formulas based on an individual horse's blood work.

G.I. Ulcer Support maintenance supplement front label from T.H.E. Equine Edge

Which ulcer symptoms does it target?

According to T.H.E. Equine Edge, gastric ulcers can show up as a sour disposition and poor appetite, sensitivity in the girth area, unwillingness to work, teeth grinding, cribbing or wind-sucking, a dull or unhealthy coat, weight loss, and colic. Because the formula also supports healthy digestion, the company says it helps address hindgut issues more effectively and efficiently, not just the stomach. The brand's shorthand: "A scoop a day keeps the ulcers away."

How do you feed and dose it?

GastroPLUS® is fed as a top-dress on the feed. For a 1,000 lb horse, give 1 level scoop per day; the recommended loading protocol is 2 level scoops a day for the first 5 days, then 1 scoop a day thereafter. A USEF and FEI compliant data sheet is available for download so competitors can verify the product against their governing-body rules. For ongoing maintenance after a course of GastroPLUS®, T.H.E. Equine Edge also offers a companion product, G.I. Ulcer Support, at $133.00.

How to buy and what it costs

GastroPLUS® starts at $172.00 and is offered in 30, 80, 160, 240, or 400-serving containers, so you can match the size to a single trial run or a full barn. Total Health Enhancement Corp offers free shipping on orders over $250 (via UPS and Usps) and backs purchases with a 45-day return, refund, or exchange satisfaction policy. Order direct from totalhealthenhance.com or reach the company toll-free at (888) 422-8398 or by; the company is based at 36 Greco Lane, Warwick, RI 02886.

Share This Solution

Facebook X LinkedIn Email

The Solution Section (FAQ)

How common are gastric ulcers in horses?

Gastric ulcers occur in the majority of horses and cause significant damage before any symptoms can be noticed. Studies indicate that 90% of all adult horses, and 50% of foals under the age of 6 months that have been scoped, have shown to have gastric ulcers.

What is GastroPLUS™ and how does it help with ulcers?

GastroPLUS™, offered by Wag-N-Will Farm, is a nutritional supplement designed to help heal and prevent gastric ulcers in horses by supporting the production of nitric oxide. Both stress and intense exercise deplete neurotransmitters crucial for adequate blood flow to the stomach, and GastroPLUS™ supplies the precursors needed to produce those neurotransmitters and increase blood flow.

Why does blood flow matter for protecting my horse's stomach?

Decreased blood flow to the stomach reduces the production of the mucus necessary to protect the stomach lining from stomach acid, and the result is ulceration of the stomach lining. By supporting nitric oxide and blood flow, GastroPLUS™ helps maintain that protective mucus layer.

How should GastroPLUS™ be fed for best results?

Because these products are amino acid compounds that go after proteins, feed on as empty a stomach as possible — food in the stomach upsets the synergy of the ingredients and renders it weak. With no food in the stomach, an insulin reaction in the small intestine delivers the full dosage of active ingredients immediately into the bloodstream; allowing the horse even small treats or to nibble on the ground only wastes the product.

How many servings does a jar provide, and how do I get dosing instructions?

Each 2 lb. jar of powder contains 32 servings for a 1000 lb. horse, where 1 ounce equals 1 serving for a 1000 lb. horse. Please email Michelle when you order to advise her of your horse's weight and condition so she can give you proper dosing instructions.

What is GastroPLUS® used for?

GastroPLUS® is an all-natural nutritional supplement formulated to aid in the healing and prevention of gastric ulcers in horses. It supports healthy digestion and gastric health and is also said to help address hindgut issues. It is made by T.H.E. Equine Edge, a brand of Total Health Enhancement Corp.

How is GastroPLUS® different from acid-blocking ulcer products?

Most ulcer products decrease the acid in a horse's stomach. GastroPLUS® instead supports the horse's own ability to produce more protective mucus in the stomach lining, which helps the horse control and contain gastric acid naturally. According to the company, acid-suppressing products can trigger rebound overproduction of acid when discontinued, turning ulcer care into a recurring cycle that GastroPLUS® is designed to avoid.

What are the active ingredients in GastroPLUS®?

It is a proprietary blend of amino acids, proteins, vitamins, and minerals. The label includes L-Arginine, L-Glutamine, L-Glutamic Acid, L-Alanine, Beta-Alanine, L-Tyrosine, L-Histidine, N-Acetyl-L-Cysteine, Papaya, Aloe, Turmeric, Bromelain, Fenugreek Seed, Choline Bitartrate, Vitamins C and E, a full B-vitamin complex, plus Zinc Gluconate, Manganese Gluconate, Iron, Selenium, and Himalayan Salt.

How do you dose GastroPLUS®?

For a 1,000 lb horse, feed it as a top-dress on the feed. The recommended protocol is 2 level scoops a day for the first 5 days, then 1 level scoop a day thereafter. A measuring scoop is included with the product.

How much does GastroPLUS® cost?

GastroPLUS® starts at $172.00. It is sold in 30, 80, 160, 240, or 400-serving containers so you can choose a short trial size or a full multi-month supply. Total Health Enhancement Corp offers free shipping on orders over $250.

What signs of ulcers does GastroPLUS® address?

T.H.E. Equine Edge associates equine ulcers with a sour disposition, poor appetite, sensitivity in the girth area, unwillingness to work, teeth grinding, cribbing or wind-sucking, a dull coat, weight loss, and colic. GastroPLUS® is designed to support the stomach and digestion to help with these issues. As the brand puts it, a scoop a day keeps the ulcers away.

Does GastroPLUS® help with hindgut problems too?

Yes. Because GastroPLUS® supports healthy overall digestion, the company says it helps address hindgut issues in a more effective and efficient way, not just the stomach. This makes it a more comprehensive digestive solution than a stomach-only product.

Is GastroPLUS® safe for competition horses?

The company provides a USEF and FEI compliant data sheet available for download, so competitors can verify the product against their governing body's rules. T.H.E. Equine Edge formulates with natural and organic ingredients and states it uses no fillers, preservatives, or added sugars.

Who makes GastroPLUS®?

GastroPLUS® is made by Total Health Enhancement Corp under its T.H.E. Equine Edge brand. The company has over 20 years of equine formulation experience and is based at 36 Greco Lane, Warwick, RI 02886.

What is the science behind T.H.E. Equine Edge formulas?

The formulas draw on Nobel Prize-winning science about Nitric Oxide, often called the Nitric Oxide Pathway. Nitric Oxide increases blood flow to damaged tissue and to tissues under high demand or stress, which supports healing and performance. The company uses precursors, flavonoid regulators, and antioxidants to help promote that effect.

Is there a maintenance product to use after GastroPLUS®?

Yes. T.H.E. Equine Edge offers G.I. Ulcer Support, a standalone preventative supplement recommended for ongoing maintenance after a course of GastroPLUS®. It is priced at $133.00 and shares many of the same digestive-support ingredients, with additions such as Spirulina, Flax Seed, and Cordyceps.

How long does it take to see results?

T.H.E. Equine Edge shows before-and-after results over roughly 4 to 6 weeks of use in its product materials. Individual horses vary, but the loading protocol of 2 scoops daily for the first 5 days is designed to get the formula working quickly before settling into the 1-scoop maintenance dose.

Is there a satisfaction guarantee?

Yes. Total Health Enhancement Corp backs purchases with a 45-day return, refund, or exchange policy. The company states its goal is to consistently provide the best products, service, and price, and to be a company you can trust and depend on.

Can I get a custom formula for my horse?

Yes. T.H.E. Equine Edge offers custom formula and blend services and can tailor a supplement based on an individual horse's blood work. The company emphasizes that each horse is different and may need a supplement specific to its needs.

What disciplines and types of horses is it used for?

Since 2010 the company has concentrated on thoroughbred and quarter horse racing, along with dressage, hunter/jumper, barrel racing, team roping, polo, reining, and pleasure riding. GastroPLUS® is intended for any horse at risk of or recovering from gastric ulcers across these disciplines.

How do I order GastroPLUS® or contact the company?

You can order GastroPLUS® directly at totalhealthenhance.com. To reach Total Health Enhancement Corp, call toll-free (888) 422-8398 or email [email protected]. The mailing address is 36 Greco Lane, Warwick, RI 02886, and orders ship via UPS and USPS.

Does GastroPLUS® contain fillers, preservatives, or sugar?

No. T.H.E. Equine Edge states that it uses natural and organic vitamins, herbs, amino acids, and minerals, and does not use fillers, preservatives, or added sugars. The formula is built around functional nutritional ingredients rather than bulking agents.