Pro-Tect™ Antimicrobial Thrush Treatment by Straight Arrow Products

Pro-Tect™ Antimicrobial Thrush Treatment — beyond everyday hoof care.

Got a horse with thrush and want an antimicrobial treatment that goes beyond the basics?

Reviewed by Ann Pruitt, InfoHorse.com · Updated May 2026

Mane 'n Tail Pro-Tect Antimicrobial Medicated Spray 32 oz bottle front by Straight Arrow Products

Pro-Tect™ Antimicrobial Thrush Treatment by Straight Arrow Products

Pro-Tect™ Antimicrobial Thrush Treatment by Straight Arrow Products

Pro-Tect™ Antimicrobial Thrush Treatment goes beyond the every day thrush treatments typically seen in todays market.

Pro-Tect™ Antimicrobial Thrush Treatment

Thrush Treatment goes beyond the everyday thrush treatment on the market today.Pro-Tect™ Antimicrobial Thrush Treatment's exclusive natural water based formula eliminates organisms associated with thrush and other hoof related diseases.

Provides full and complete treatment for the entire hoof
Deep penetrating gel formula assures complete and effective treatment
Kills the bacteria associated with thrush
Kills other opportunistic bacteria and fungi
Non-drying, non-flammable, non-staining
Pleasant fragrance

Where Can I Buy Pro-Tect Antimicrobial Thrush Treatment?
All Straight Arrow products are available
JeffersEquine, ValleyVet, DoverSaddlery, SmartPak
and at most feed and tack stores- so be sure to pick up yours today!

What exactly is Pro-Tect™ Antimicrobial Thrush Treatment?

Pro-Tect™ Thrush Treatment is a veterinary-strength, deep-penetrating gel that targets the bacteria and fungi responsible for thrush and other hoof-related diseases. Unlike harsh, caustic thrush remedies that rely on copper sulfate or formaldehyde, Pro-Tect uses an exclusive natural water-based formula that treats the entire hoof rather than just the surface of the frog. It is one product in the broader Mane ’n Tail Pro-Tect veterinary line, which also includes a medicated shampoo, a skin-and-wound spray, and a wound cream. The thrush formula is sold in a 16 oz. bottle.

Mane 'n Tail Pro-Tect Antimicrobial Medicated Spray 32 oz bottle back label directions

Who makes it, and what is the company’s pedigree?
Pro-Tect is made by Straight Arrow Products, Inc., the family-owned maker of the original Mane ’n Tail® brand. The company was founded in 1970 by Philip and Bonnie Katzev, who ran one of the largest Arabian horse-breeding operations on the East Coast and originally developed Mane ’n Tail Conditioner for their own horses’ manes and tails. Today the company is led by second-generation owner and president Devon B. Katzev and is headquartered in Bethlehem, Pennsylvania, with products sold in more than 175,000 locations across North America and internationally. Their guiding credo since 1970 has been simply “Satisfy the Customer.”

Mane 'n Tail Pro-Tect Antimicrobial Medicated Shampoo 32 oz bottle front by Straight Arrow Products

What is in the formula and why does it matter?

The active ingredient is Benzalkonium chloride 0.75% delivered in an exclusive Quatracin conditioning base (per the FDA DailyMed label, NDC 62001-0334). Benzalkonium chloride is a broad-spectrum quaternary-ammonium antimicrobial that kills the opportunistic bacteria and fungi associated with thrush, while the Quatracin base conditions rather than dries the tissue. Because the formula is water-based, it will not burn, sting, stain, or dry out the hoof the way traditional acidic or solvent-based thrush products can, and it is non-flammable with a pleasant scent.

Mane 'n Tail Pro-Tect Antimicrobial Medicated Shampoo 32 oz bottle back label

How do you apply it?

The label directions are straightforward: clean the hoof thoroughly of dirt and debris, then apply Pro-Tect directly onto the hoof, working it daily into all crevices and skin areas to assure thorough coverage. Massage it in by hand or with a brush where possible, then leave the product on the hoof — do not wash it off. It is applied once or twice daily as needed until the affected area is healed. The treatment is for external veterinary use only and should not be mixed with other medicated thrush treatments, as combining products can reduce its effectiveness.

Why do horse owners and farriers choose Pro-Tect over older thrush remedies?

Many traditional thrush treatments are dark, staining, and caustic enough to damage healthy frog tissue, which can slow recovery. Pro-Tect was formulated to go beyond those everyday products: it provides full and complete treatment for the entire hoof, kills the bacteria and fungi linked to thrush, and does so while being non-drying, non-flammable, and non-staining. The gel consistency clings to the frog clefts and central sulcus where thrush hides, and the conditioning base supports healthier tissue as the infection clears, making it suitable for repeated daily use during a treatment cycle.

How and where can you buy it?

Pro-Tect Thrush Treatment is carried by major equine and farrier retailers including Chewy, Anvil Brand (16 oz., SKU 70-064, around $11.60), Big D’s, PBS Animal Health, and Heritage Animal Health, and the full Mane ’n Tail Pro-Tect line is featured on the official site at manentailequine.com. For product questions you can reach Straight Arrow Products directly. On the official store, companion Pro-Tect products such as the Antimicrobial Medicated Spray and Medicated Shampoo (32 oz.) retail for $16.99 each.

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The Solution Section (FAQ)

What is Pro-Tect™ Antimicrobial Thrush Treatment?

Pro-Tect™ Antimicrobial Thrush Treatment by Straight Arrow Products is a hoof-care treatment that goes beyond the everyday thrush treatments on the market today. Its exclusive natural water-based formula eliminates the organisms associated with thrush and other hoof-related diseases.

How does Pro-Tect™ work on thrush?

It kills the bacteria associated with thrush and also kills other opportunistic bacteria and fungi. The deep-penetrating gel formula assures complete and effective treatment, providing full and complete coverage for the entire hoof.

Will Pro-Tect™ dry out or stain my horse's hoof?

No. Pro-Tect™ is non-drying, non-flammable, and non-staining. It also has a pleasant fragrance, so it can treat thrush while remaining gentle on the hoof.

Is Pro-Tect™ only for thrush, or does it help with other hoof problems?

While it is formulated to treat thrush, the same water-based formula eliminates organisms associated with other hoof-related diseases. It targets opportunistic bacteria and fungi as well, treating the entire hoof rather than just one spot.

Where can I buy Pro-Tect™ Antimicrobial Thrush Treatment?

All Straight Arrow products are available at JeffersEquine, ValleyVet, DoverSaddlery, and SmartPak, as well as at most feed and tack stores. So be sure to pick up yours today.

Who makes Pro-Tect™ Antimicrobial Thrush Treatment?

Pro-Tect™ Antimicrobial Thrush Treatment is made by Straight Arrow Products, based at 900 Conroy Place, Easton, Pennsylvania 18040. All Straight Arrow products are available at major feed and tack stores.

How can I reach Straight Arrow Products with questions about Pro-Tect™?

You can contact Straight Arrow Products directly by phone at 1-800-827-9815 or by email at [email protected]. Reach out with any questions about using Pro-Tect™ Antimicrobial Thrush Treatment on your horse's hooves.

What is Pro-Tect Antimicrobial Thrush Treatment used for?

It is a veterinary-strength gel used to treat thrush and other hoof-related diseases in horses. It eliminates the opportunistic bacteria and fungi associated with thrush and provides full, complete treatment of the entire hoof rather than just the surface of the frog.

What is the active ingredient in Pro-Tect Thrush Treatment?

According to the FDA DailyMed label (NDC 62001-0334), the active ingredient is Benzalkonium chloride 0.75% in an exclusive Quatracin conditioning base. Benzalkonium chloride is a broad-spectrum quaternary-ammonium antimicrobial that kills the bacteria and fungi linked to thrush, while the Quatracin base conditions the tissue.

Who makes Pro-Tect Thrush Treatment?

It is made by Straight Arrow Products, Inc., the family-owned company behind the original Mane 'n Tail brand. The company was founded in 1970 and is headquartered in Bethlehem, Pennsylvania.

How do I apply Pro-Tect Thrush Treatment?

Clean the hoof thoroughly of dirt and debris first, then apply Pro-Tect directly onto the hoof. Work it daily into all crevices and skin areas to assure thorough coverage, massaging it in by hand or with a brush where possible. Leave the product on the hoof and do not wash it off; apply once or twice daily until the area is healed.

How is Pro-Tect different from traditional thrush treatments?

Many traditional thrush remedies are caustic, dark, and staining, and can damage healthy frog tissue. Pro-Tect uses an exclusive natural water-based formula that is non-drying, non-flammable, and non-staining; it will not burn or sting, and it conditions the tissue while it kills the organisms associated with thrush.

What size does Pro-Tect Thrush Treatment come in?

The thrush treatment is sold in a 16 oz. bottle (480 g per the FDA label). It is a deep-penetrating gel formula designed to cling to the frog clefts and central sulcus where thrush hides.

How much does Pro-Tect Thrush Treatment cost?

Pricing varies by retailer. Farrier supplier Anvil Brand lists the 16 oz. Mane 'n Tail Vet Strength Pro-Tect Thrush Treatment (SKU 70-064) at around $11.60. It is also carried by Chewy, Big D's, PBS Animal Health, and Heritage Animal Health, so prices can differ between stores.

Is Pro-Tect safe to use daily?

Yes. The water-based, non-drying formula is intended for daily application as part of a treatment cycle, applied once or twice daily as needed until the affected area is healed. Because it does not burn or dry out the hoof, it is well suited to repeated use during recovery.

Will Pro-Tect stain my horse or my hands?

No. Pro-Tect is specifically formulated to be non-staining, unlike many traditional dark thrush treatments. It is also non-flammable and has a pleasant scent, making it more comfortable to apply than caustic or solvent-based products.

Can Pro-Tect be used together with other thrush products?

No. The label warns that you should not mix Pro-Tect with other medicated thrush treatments, and that its effectiveness may be reduced if used in conjunction with other shampoo or treatment products. It is best used on its own for a clean, complete treatment.

Is Pro-Tect Thrush Treatment safe for all animals?

It is for external veterinary use only and is labeled for horses and other animals with hoof problems, but it is NOT for use on cats or puppies. As with any treatment, consult a veterinarian if any problems persist or are of concern.

What causes thrush in horses, and how does Pro-Tect address it?

Thrush is a bacterial and fungal infection of the frog and hoof clefts, most common in damp, dirty, or poorly cleaned environments where the hoof stays wet. Pro-Tect's benzalkonium chloride antimicrobial kills the opportunistic bacteria and fungi responsible, while its gel consistency penetrates deep into the affected crevices for a complete treatment.

Does Pro-Tect Thrush Treatment require a prescription?

No, it is an over-the-counter topical veterinary product sold through tack shops, farrier suppliers, and pet retailers. It carries an FDA DailyMed label but is not a prescription drug; it is intended for external use on the hoof.

What other products are in the Mane 'n Tail Pro-Tect line?

Besides the Thrush Treatment, the Pro-Tect veterinary line includes an Antimicrobial Medicated Shampoo (32 oz., about $16.99 on the official site), an Antimicrobial Medicated Skin & Wound Spray (32 oz., about $16.99), and a Wound Cream. The shampoo and spray are commonly used on rain rot, scurf, ringworm, scratches, hot spots, and skin rashes.

Where can I buy Pro-Tect Thrush Treatment?

It is available from major equine and farrier retailers including Chewy, Anvil Brand, Big D's, PBS Animal Health, and Heritage Animal Health. The full Mane 'n Tail Pro-Tect line is featured at the official site, manentailequine.com.

How do I contact Straight Arrow Products about Pro-Tect?

You can reach Straight Arrow Products by phone at 1-800-827-9815 for product questions. The company is based at its corporate headquarters and manufacturing plant in Bethlehem, Pennsylvania, and operates the official Mane 'n Tail Equine website at manentailequine.com.

What is the history behind Mane 'n Tail and Straight Arrow Products?

Straight Arrow Products was founded in 1970 by Philip and Bonnie Katzev, who ran a large Arabian horse-breeding operation and created the original Mane 'n Tail Conditioner for their own horses. The brand later expanded into human hair care after riders discovered it worked on people too. The company is now run by second-generation owner and president Devon B. Katzev and its products are sold in over 175,000 locations across North America and beyond.